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Home › Medications › fresh frozen plasma

fresh frozen plasma

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of fresh frozen plasma

6 trials tracked of fresh frozen plasma: 4 in phase 3 or 4.

6Trials tracked
4Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 3 3 Other / NA 2
  1. Phase 4 Prospective Validation of a Plasma Transfusion Dosing Algorithm in Patients With Chronic Liver Disease Completed
  2. Phase 3 Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures Completed
  3. Phase 3 Efficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant Therapy Completed
  4. Phase 3 An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Procedure Completed
  5. N/A Decision Support for Intraoperative Low Blood Pressure Completed
  6. N/A The Effect of Prophylactic FFP Administration on ECMO Circuit Longevity Completed

Showing the 6 most-cited and recently-updated of 6 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Prothrombin complex concentrate reduces reoperation for bleeding and chest tube drainage after cardiac surgery
Drug Pipeline Meta-analysis
Prothrombin complex concentrate reduces reoperation for bleeding and chest tube drainage after cardiac surgery Prothrombin Complex Concentrate May Reduce Bleeding After Cardiac Surgery
This meta-analysis of 711 patients indicates that prothrombin complex concentrate may reduce reoperation rates and chest tube drainage compa…
Prothrombin complex concentrate may lower the risk of bleeding and the need for reoperation in patients following cardiac surgery.
Frontiers Sep 15, 2026
Fresh-frozen plasma shows no protective effect against intraventricular hemorrhage in preterm infants
Neurology RCT
Fresh-frozen plasma shows no protective effect against intraventricular hemorrhage in preterm infants Trial Shows Fresh Frozen Plasma Does Not Prevent Brain Bleeding
In a target trial emulation of 748 preterm infants (gestational age ≤34 weeks) with prolonged aPTT (≥70 s), fresh-frozen plasma transfusion …
A study of 748 preterm infants found that fresh-frozen plasma transfusions did not provide a protective effect against intraventricular hemo…
Frontiers Sep 10, 2026
Brodifacoum poisoning can trigger life-threatening aortic dissection and severe coagulopathy
Orthopedics & Sports Medicine Sys. Review
Brodifacoum poisoning can trigger life-threatening aortic dissection and severe coagulopathy Rodenticide poisoning can lead to life-threatening aortic artery tears
This case report and pathophysiological review describes a 69-year-old man who developed an aortic dissection following brodifacoum poisonin…
A man's severe rodenticide poisoning caused a dangerous tear in his main artery, highlighting the risks of certain chemicals on blood clotti…
Frontiers Aug 19, 2026