PPSS shows rapid metastatic progression despite neoadjuvant Adriamycin, Ifosfamide, and Mesna
Case Report Details Aggressive Synovial Sarcoma After Treatment
This case report describes a 60-year-old woman with primary pulmonary synovial sarcoma who received neoadjuvant Adriamycin, Ifosfamide, and …
A 60-year-old woman's synovial sarcoma shrank with chemo, but spread widely just four months after surgery.
Biochemical marker decline may not indicate clinical stability in intracranial growing teratoma syndrome
Tumor Markers Drop But Mass Grows: A Case Report
This case report describes two pediatric patients with suprasellar mixed germ cell tumors who experienced biochemical success despite radiol…
In two children with brain germ cell tumors, tumor markers fell sharply while the tumor itself enlarged, a rare condition called growing ter…
Pleuropulmonary blastoma diagnosed after initial rhabdomyosarcoma interpretation in a 2-year-old boy
Case report shows rare lung cancer in toddler with DICER1
This case report describes a 2-year-old boy with a thoracic mass initially interpreted as embryonal rhabdomyosarcoma, later diagnosed as ple…
A toddler’s lung tumor was reclassified as a rare cancer linked to DICER1 syndrome, changing his treatment and highlighting a key diagnosis …
Interval-compressed VDC/IE protocol feasibility and outcomes in 27 Ewing's sarcoma patients at a North African center
Compressed chemotherapy showed mixed results for Ewing's sarcoma patients in a small study.
This retrospective, single-institutional cohort study evaluated an interval-compressed VDC/IE protocol in 27 patients with Ewing's sarcoma t…
A small study found that a compressed chemotherapy regimen for Ewing's sarcoma had high toxicity and low survival rates.
Literature review on primary CNS MALT lymphoma treatment and diagnosis
A Rare Brain Tumor in the Ventricles Was Found and Treated
This literature review and case report describes a 62-year-old man with primary central nervous system mucosa-associated lymphoid tissue lym…
A 62-year-old man had a rare brain tumor inside a fluid-filled ventricle, and a new treatment plan kept it from coming back.
Early study of CDP1 plus chemotherapy showed promising activity and manageable safety in advanced penile cancer
New Drug Combo Shrinks Advanced Penile Cancer Tumors
This prospective phase 1 study evaluated the safety and antitumor activity of CDP1 monotherapy or in combination with standard chemotherapy …
A new drug combo shrinks advanced penile cancer tumors, offering fresh hope for patients with rare, hard-to-treat disease.
Durvalumab plus chemotherapy shows 35% response in phase II trial for metastatic pulmonary sarcomatoid carcinoma
Small study tests drug combination for rare, aggressive lung cancer
A phase II single-arm trial in 20 patients with recurrent/metastatic pulmonary sarcomatoid carcinoma evaluated durvalumab plus doxorubicin/i…
A rare lung cancer drug combo shrank tumors in 35% of patients, offering hope for those with this aggressive disease despite common side eff…
Case report describes multimodal treatment and single-cell sequencing in NF1 patient with Malignant Triton Tumor
What happens when a rare cancer returns? One young woman's story offers a clue
A case report describes a 23-year-old woman with neurofibromatosis type 1 and Malignant Triton Tumor.
A 23-year-old woman with a rare chest tumor found disease stabilization after surgery failed, using a mix of chemotherapy, targeted therapy,…