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Patient Mode — summaries use plain language, avoiding clinical jargon.
Nutrition & Obesity Medicine
Sys. Review
NAD+ repletion via NMN or NR shows context-dependent effects on muscle stem cell homeostasis and sarcopenia
NAD+ boosters may help muscle stem cells fight aging weakness
This systematic review synthesizes nearly 60 representative preclinical and clinical studies on NAD+ repletion for sarcopenia. The authors d…
A review of nearly 60 studies suggests NAD+ precursors like NMN or NR could support muscle stem cells and reduce oxidative stress in sarcope…
Frontiers
Jun 5, 2026
Pediatrics
RCT
Nicotinamide Riboside Plus Exercise Improves Fitness in Friedreich's Ataxia
Combining exercise and nicotinamide riboside improved fitness in Friedreich's ataxia patients
This phase 2 randomized trial in 66 individuals with Friedreich's ataxia found that 12 weeks of nicotinamide riboside plus exercise increase…
A 12-week trial found that combining exercise with nicotinamide riboside improved heart and lung fitness in people with Friedreich's ataxia.
May 1, 2026
Drug Pipeline
RCT
Nicotinamide riboside and NAD+ injections show preliminary safety in healthy participants
Nicotinamide Riboside Injections Are Safe But Cause Mild Pain
This Phase 1 RCT in healthy participants assessed bolus injections of nicotinamide riboside or NAD+. The study found 100% participant retent…
New injection data shows Nicotinamide Riboside is safe but causes mild pain and soreness for most people.
medRxiv
May 1, 2026