Germline variants associated with chemotherapy-induced peripheral neuropathy show poor replication and limited clinical translation
Genetic Variations Linked to Chemotherapy Induced Nerve Damage
This systematic review of 72 studies assessed germline genetic variations related to vincristine, taxanes, platinum agents, and bortezomib. …
Specific genetic markers may be linked to nerve damage caused by chemotherapy, though these findings are not yet ready for use in clinical p…
Neurotoxic chemotherapy causes moderate to large increases in vibration perception threshold in hands and feet
Chemotherapy Linked to Loss of Sensation in Hands and Feet
This meta-analysis of 1635 patients receiving neurotoxic chemotherapy found significant increases in vibration perception threshold (VPT) in…
New analysis shows that certain chemotherapy drugs can cause a significant loss of sensation in the hands and feet for many patients.
Review covers capecitabine and trastuzumab emtansine for triple-negative and HER2-positive breast cancer
Breast Cancer Chemo Is Getting Smarter and More Effective
This narrative review examines emerging therapies for women with breast cancer, including triple-negative and HER2-positive disease. The aut…
New blood tests and tumor markers are helping doctors choose the right chemo for breast cancer, reducing resistance and improving survival.