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Neurology
RCT
Ponesimod maintains low disease activity and safety in RRMS over 13 years
Trial Shows Ponesimod Maintains Safety for Relapsing-Remitting Multiple Sclerosis
This Phase 2b randomized controlled trial of 393 participants with relapsing-remitting multiple sclerosis found that ponesimod (10, 20, or 4…
A clinical trial shows that patients with relapsing-remitting multiple sclerosis can stay on ponesimod for up to 13 years with consistent re…
Oct 1, 2026
Neurology
RCT
Ponesimod Shows Sustained Efficacy and Safety in RMS Over 5 Years
Could Ponesimod Change the Game for Multiple Sclerosis Patients?
In a 5-year extension of the OPTIMUM study, ponesimod 20 mg maintained a lower ARR (0.143) compared to teriflunomide switchers (0.184).
After five years, nearly half of people taking ponesimod for multiple sclerosis had no relapses, offering more stable lives with fewer unexp…
Mar 27, 2026