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Home › Medications › seltorexant

seltorexant

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of seltorexant

2 trials tracked of seltorexant: 1 in phase 3 or 4.

2Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 1
  1. Phase 3 A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant Completed
  2. Phase 2 A Study of Seltorexant in Participants With Probable Alzheimer's Disease Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Seltorexant vs Quetiapine-XR for MDD: Similar Discontinuation, Numeric MADRS Benefit at Lower Dose
Psychiatry RCT
Seltorexant vs Quetiapine-XR for MDD: Similar Discontinuation, Numeric MADRS Benefit at Lower Dose New Drug Helps Depression When Sleep Is Lost
An exploratory phase 2 RCT compared adjunctive seltorexant (20/40 mg) to quetiapine-XR (150/300 mg) in SSRI/SNRI-inadequate responders with …
A new sleep drug helps lift depression without the weight gain or dizziness often caused by older treatments for patients who struggle to re…
Apr 13, 2026