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Home › Medications › sulfadoxine-pyrimethamine

sulfadoxine-pyrimethamine

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of sulfadoxine-pyrimethamine

4 trials tracked of sulfadoxine-pyrimethamine: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 64 citations.

4Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 2 Phase 2 1 Other / NA 1
  1. Phase 3 Intermittent Preventive Treatment of Malaria in Schoolchildren Completed · 64 cited
  2. Phase 3 Chloroquine for Malaria in Pregnancy Completed
  3. Phase 2 Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine Completed
  4. N/A Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 Completed

Showing the 4 most-cited and recently-updated of 4 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
SP+AQ cuts malaria incidence 54.6% versus SP alone in African children
Infectious Disease Sys. Review
SP+AQ cuts malaria incidence 54.6% versus SP alone in African children Adding amodiaquine to sulfadoxine-pyrimethamine reduces malaria in children
This meta-analysis of 32 sites across 13 African countries found that sulfadoxine-pyrimethamine plus amodiaquine (SP+AQ) reduced malaria inc…
Combining two medicines significantly lowers malaria rates in children across Africa compared to using only one drug.
medRxiv Jul 19, 2026
Cross-sectional analysis links SP resistance polymorphisms to gametocyte carriage in Mozambican malaria isolates
Infectious Disease
Cross-sectional analysis links SP resistance polymorphisms to gametocyte carriage in Mozambican malaria isolates Malaria Resistance in Mozambique Is Rising Fast
This cross-sectional molecular analysis examined 100 P.
Malaria parasites in Mozambique are becoming resistant to the main pregnancy drug, increasing the risk of low birth weight and stillbirth fo…
medRxiv Apr 10, 2026