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Rheumatology
RCT
Tegileridine 0.5 mg reduces fentanyl-induced cough incidence from 28.7% to 11.1%
Tegileridine reduces coughing during surgery after fentanyl injection
This randomized controlled trial of 216 adults undergoing elective surgery found that tegileridine 0.5 mg significantly reduced the incidenc…
A new treatment may help patients avoid painful and uncomfortable coughing immediately after receiving pain medication before surgery.
Frontiers
Jul 19, 2026
Anesthesiology & Pain Medicine
Meta-analysis
Tegileridine provides superior analgesic efficacy over placebo for postoperative acute pain with a favorable safety profile
Tegileridine shows promise for managing pain after surgery
This meta-analysis of 1,011 patients evaluated tegileridine for postoperative acute pain. Tegileridine significantly reduced rSPID24 and rSP…
A new medication called tegileridine may offer a way to manage severe pain after surgery with fewer side effects like nausea and vomiting.
Frontiers
Jul 5, 2026