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tolvaptan

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of tolvaptan

21 trials tracked of tolvaptan: 16 in phase 3 or 4 and 7 with published results. The most-cited published study has 234 citations.

21Trials tracked
16Phase 3 & 4
0Recruiting
7With published results
Phase distribution
Phase 4 7 Phase 3 9 Phase 2 3 Other / NA 2
  1. Phase 3 Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure Completed · 234 cited
  2. Phase 4 Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure Completed · 179 cited
  3. Phase 3 Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease Completed · 43 cited
  4. Phase 3 Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease) Completed · 38 cited
  5. Phase 3 Tolvaptan Extension Study in Participants With ADPKD Completed · 38 cited
  6. Phase 3 A Study to Investigate the Long-term Safety and Efficacy of Tolvaptan in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Trial 156-04-251 in Japan] Completed · 19 cited
Show 15 more trials
  1. Phase 3 Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Completed · 11 cited
  2. Phase 4 Pilot Study of Using Copeptin to Predict Response to Tolvaptan Completed
  3. Phase 4 Aquaresis Utility for Hyponatremic Acute Heart Failure Study Completed
  4. Phase 4 Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients Completed
  5. Phase 4 Tolvaptan in Hyponatremic Cancer Patients Completed
  6. Phase 4 Tolvaptan For Worsening Outpatient Heart Failure: Role of Copeptin In Identifying Responders Completed
  7. Phase 4 Tolvaptan for Ascites in Cirrhotic Patients Completed
  8. Phase 3 Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload Completed
  9. Phase 3 International, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia Completed
  10. Phase 3 Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients Completed
  11. Phase 2 A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Completed
  12. Phase 2 Short-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD) Completed
  13. Phase 2 Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Completed
  14. N/A TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study Completed
  15. N/A Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD Completed

Showing the 21 most-cited and recently-updated of 21 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

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