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Home › Medications › tucatinib

tucatinib

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of tucatinib

5 trials tracked of tucatinib: 1 in phase 3 or 4.

5Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 4
  1. Phase 3 Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer Completed
  2. Phase 2 A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer Completed
  3. Phase 2 A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response Completed
  4. Phase 2 A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer Completed
  5. Phase 2 Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer Completed

Showing the 5 most-cited and recently-updated of 5 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Tucatinib plus trastuzumab and pertuzumab improves median PFS to 24.9 months in HER2+ MBC
Oncology RCT
Tucatinib plus trastuzumab and pertuzumab improves median PFS to 24.9 months in HER2+ MBC Trial shows Tucatinib improves progression-free survival for metastatic breast cancer
This Phase III randomized controlled trial of 654 patients with HER2+ metastatic breast cancer found that adding tucatinib to trastuzumab an…
Adding tucatinib to a standard two-drug combination may help patients with HER2+ metastatic breast cancer live longer without their disease …
Jun 12, 2026