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Home › Medications › vandetanib

vandetanib

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of vandetanib

15 trials tracked of vandetanib: 4 in phase 3 or 4.

15Trials tracked
4Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 4 Phase 2 10 Phase 1 1
  1. Phase 3 Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment Completed
  2. Phase 3 Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy Completed
  3. Phase 3 Efficacy Study Comparing ZD6474 in Combination With Pemetrexed and Pemetrexed Alone in 2nd Line NSCLC Patients Completed
  4. Phase 3 ZACTIMA (an Anti-EGFR / Anti-VEGF Agent) Combined With Docetaxel Compared to Docetaxel in Non-small Cell Lung Cancer Completed
  5. Phase 2 Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors Completed
  6. Phase 2 Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer Completed
Show 9 more trials
  1. Phase 2 S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Completed
  2. Phase 2 A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients Completed
  3. Phase 2 Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions Completed
  4. Phase 2 A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer Completed
  5. Phase 2 Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC) Completed
  6. Phase 2 Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet Chemotherapy Completed
  7. Phase 2 Randomized Study of Docetaxel +/- Vandetanib in Metastatic TCC Completed
  8. Phase 2 Vandetanib to Treat Children and Adolescents With Medullary Thyroid Cancer Completed
  9. Phase 1 A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery Completed

Showing the 15 most-cited and recently-updated of 15 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Selpercatinib tops cabozantinib and vandetanib for PFS in advanced medullary thyroid cancer
Diabetes & Endocrinology Meta-analysis
Selpercatinib tops cabozantinib and vandetanib for PFS in advanced medullary thyroid cancer Selpercatinib Shows Better Survival for Advanced Medullary Thyroid Cancer
A network meta-analysis of 1,076 patients with advanced medullary thyroid cancer found selpercatinib superior to cabozantinib and vandetanib…
A new analysis of 1,076 patients suggests selpercatinib may offer better progression-free survival than other treatments for medullary thyro…
Frontiers Jun 22, 2026