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Extended sleep improved sleep metrics but did not change insulin sensitivity in a small trial.

Extended sleep improved sleep metrics but did not change insulin sensitivity in a small trial.
Photo by Vitaly Gariev / Unsplash
Key Takeaway
Consider that extended sleep improves sleep metrics but may not improve insulin sensitivity in this population.

The trial examined the impact of extended sleep versus habitual sleep on metabolic parameters in individuals with overweight, obesity, insulin resistance, and short sleep schedules. Participants in the extended sleep group spent more time in bed and achieved greater increases in sleep duration compared to the control group. Subjective measures of sleep health and day-to-day variability in sleep also improved more in the extended sleep group.

Despite these improvements in sleep metrics, the study observed no differences between groups regarding multiorgan insulin sensitivity or glycemic control. The primary outcome of interest, which included hepatic and adipose tissue insulin sensitivity, showed no benefit from the intervention. Secondary outcomes related to blood sugar regulation similarly failed to show a significant advantage for the extended sleep approach.

The authors note that the small number of participants and the brief duration of the study limit the ability to draw firm conclusions. Safety was not a primary focus as adverse events were not reported. Clinicians should interpret these results with caution, recognizing that extended sleep may improve sleep quality without necessarily resolving underlying metabolic dysfunction in this specific population.

Study Details

Study typeRct
Sample sizen = 15
EvidenceLevel 2
Follow-up1.4 mo
PublishedMay 2026
View Original Abstract ↓
OBJECTIVE: To determine whether extending sleep improves insulin sensitivity in people with overweight or obesity, insulin resistance, and habitual short sleep schedules (<7 h/night). RESEARCH DESIGN AND METHODS: Participants were randomized to habitual sleep (HS) (n = 15) or extended sleep (ES) (n = 14) for ∼6 weeks. Multiorgan (whole-body [primarily muscle], hepatic, and adipose tissue) insulin sensitivity (assessed by the hyperinsulinemic-euglycemic clamp procedure with tracer infusions) and glycemic control (assessed by 24-h serial plasma glucose and insulin concentrations during wakefulness) were determined. RESULTS: Time in bed and sleep duration increased more in the ES group (1.3 ± 0.6 and 1.1 ± 0.5 h/night) than in the HS group (0.3 ± 0.8 and 0.0 ± 0.4 h/night). Day-to-day variability in sleep and subjective measures of sleep health improved more in the ES than HS group, without differences in multiorgan insulin sensitivity or glycemic control between groups. CONCLUSIONS: Extending sleep by ∼1 h/night for ∼6 weeks in people with overweight or obesity and short sleep schedules improves sleep health but not insulin sensitivity or glycemic control.
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