Scientists looked at DNA from thousands of Russian people to find links between genes and heart health. They studied how certain gene changes affect total cholesterol, bad LDL cholesterol, and good HDL cholesterol levels. This helps understand why some people get heart disease while others do not.
The researchers found many gene spots connected to cholesterol. Some of these spots are in genes that the body uses to make or move fats around. Knowing which genes are active helps explain a person's natural risk for atherosclerosis and heart attacks.
Men and women had different genetic patterns for cholesterol. For example, some gene changes only raised cholesterol risk in women. This shows that heart disease risk is not the same for everyone and depends on sex.
Using these genetic profiles allows for better long-term health checks. Doctors can use this information to spot high-risk patients early and start prevention plans sooner.