A major review looked at data from almost three thousand adults who had a stroke. The team checked a specific inflammation marker called SII right after the stroke happened. They compared people with high levels of this marker to those with lower levels.
Patients with higher SII scores were much more likely to feel depressed later on. About eight hundred twenty two people in the group developed post-stroke depression. The study showed that high inflammation was connected to a significantly greater risk of this mood problem.
The link between inflammation and depression held true across different types of strokes and ages. It did not matter if the study was small or large. This finding suggests that checking SII levels is a useful way to find patients at risk early.
Doctors might use this simple test to identify who needs extra support. Finding these patients sooner could lead to better treatment plans and improved recovery for everyone affected by a stroke.