High SII at admission linked to 2.14-fold increased risk of post-stroke depression
High SII levels at admission linked to higher stroke depression risk in adults
This meta-analysis of 2,780 adult stroke patients found that a high systemic immune-inflammation index (SII) at admission was significantly …
A large review of nearly three thousand stroke patients found that higher inflammation markers at admission doubled the chance of developing…
Systematic review and meta-analysis of mindfulness for post-stroke depression
Mindfulness cuts depression after stroke for many patients
This systematic review and meta-analysis of 469 post-stroke patients found mindfulness-based stress reduction significantly reduced depressi…
Stroke survivors who practice mindfulness may see meaningful drops in depression, especially during stable recovery, though results vary by …
Network meta-analysis finds exercise therapies reduce depressive symptoms in post-stroke depression
Exercise therapies reduce depression and improve function after stroke
This systematic review and network meta-analysis of 2,339 patients found that various exercise therapies significantly reduce depressive sym…
A network meta-analysis of nearly 2,400 patients found exercise therapies significantly reduce depressive symptoms and improve daily living …
Acupuncture plus wet cupping therapy versus acupuncture-only for post-stroke depression
Acupuncture plus wet cupping therapy helps mild-to-moderate post stroke depression more than acupuncture alone
This randomized controlled trial in 130 patients with mild-to-moderate post-stroke depression compared acupuncture plus wet cupping therapy …
Adding wet cupping therapy to acupuncture reduced depression scores more than acupuncture alone in people with mild-to-moderate post stroke …
Abdominal acupuncture added to tDCS improves post-stroke depression in randomized trial
Abdominal acupuncture plus tDCS showed better results than tDCS alone for post-stroke depression in a small trial
In a randomized trial of 126 patients with post-stroke depression (90 analyzed after 1:1 propensity score matching), abdominal acupuncture a…
Adding abdominal acupuncture to standard tDCS therapy improved depression, daily function, and sleep quality in stroke patients more than tD…
Research across Stroke
Related studies from across the Stroke family.
Tirofiban Adjunct Therapy Improves Outcomes in Patients with Inadequate Tenecteplase Response
Trial shows tirofiban improves outcomes for some stroke patients
Intravenous tirofiban significantly improves 90-day functional outcomes for acute ischemic stroke patients failing initial tenecteplase ther…
A new clinical trial suggests that adding tirofiban can improve recovery rates for certain types of stroke patients who do not respond well …
Mind-body training improves upper-limb function after stroke, optimal dose near 33.5 hours
Mind body training improves arm function for stroke survivors
This meta-analysis of 16 RCTs (769 participants) found that mind-body training (MBT), including Tai Chi, significantly improves upper-limb f…
New data shows that mind body exercises like Tai Chi can significantly improve arm movement and function for people recovering from a stroke…
Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
New strategy helps manage heart blood clots after heart attack
This case report describes an individualized six-phase antithrombotic strategy for a 27-year-old male with myocardial infarction, stroke, hy…
A tailored six-phase treatment plan helped a young man recover fully from a stroke and heart attack while successfully clearing dangerous bl…
Brain-computer interface training improves global cognitive function in stroke survivors with SMD=0.62
Brain computer interface training improves cognitive function after stroke
This systematic review and meta-analysis of randomized controlled trials indicates that brain-computer interface (BCI) training significantl…
New data shows that brain-computer interface training can improve focus and daily tasks for people recovering from a stroke.
Acupuncture shows consistent signals for dysphagia and depressive symptoms after ischemic stroke
Acupuncture May Help Stroke Patients with Swallowing and Mood
This narrative review synthesizes evidence on acupuncture for ischemic stroke. It finds more consistent signals for dysphagia and depressive…
New research suggests acupuncture may specifically help stroke patients manage swallowing difficulties, depression, and cognitive issues.
Repetitive transcranial magnetic stimulation may enhance upper limb motor function following a stroke
Magnetic stimulation may help arm movement after a stroke
This overview of systematic reviews analyzed 17 meta-analyses and systematic reviews regarding repetitive transcranial magnetic stimulation …
A review of several studies suggests that magnetic brain stimulation could improve arm movement for people recovering from a stroke.
Localized AI and policy frameworks address structural barriers to stroke care in low-income countries
New strategy aims to improve stroke care in developing regions
This narrative review explores the integration of lightweight AI models into stroke care within resource-constrained settings. The authors p…
A new framework suggests using specialized AI models to overcome staffing shortages and broken care paths for stroke patients in low-income …
Meta-analysis shows tirofiban improves functional independence but raises intracranial hemorrhage risk in acute ischemic stroke patients
Tirofiban improves stroke recovery but raises bleeding risk
A meta-analysis of 4,210 patients found tirofiban increased functional independence at 90 days compared to conventional management. However,…
A review of 4210 patients finds tirofiban boosts functional independence after stroke but increases bleeding risk.
Endothelial ferroptosis blockade targets ischemic stroke and neurodegenerative conditions in brain microvascular endothelial cells
Ferroptosis blockade risks in brain microvascular endothelial cells need evaluation
This narrative review discusses endothelial ferroptosis blockade as a potential strategy for ischemic stroke, neurodegenerative conditions, …
A review suggests blocking ferroptosis in brain cells requires more study before use in stroke or neurodegenerative disease patients.
Remote transitional care improves depressive symptoms in stroke patients, meta-analysis finds
Remote care helps stroke patients feel less depressed
A meta-analysis of 6 randomized controlled trials found that remote transitional care significantly improved depressive symptoms in stroke p…
A meta-analysis of six trials found remote transitional care significantly reduced depressive symptoms in stroke patients, though effects on…
Tenecteplase before EVT shows no functional benefit over EVT alone in late window stroke
Tenecteplase before clot removal did not improve stroke outcomes in this trial
A phase 3 trial found that intravenous tenecteplase before endovascular therapy did not improve functional independence at 90 days compared …
A large trial found giving tenecteplase before clot removal did not improve stroke recovery or safety compared to clot removal alone.
Triple Pill Therapy Lowers Recurrent Stroke Incidence in Patients With Prior Intracerebral Hemorrhage
Single pill with three blood pressure drugs cuts stroke risk after brain bleed
This multinational randomized controlled trial enrolled 1670 patients with a history of intracerebral hemorrhage and baseline systolic blood…
A single pill combining three low-dose blood pressure drugs reduced recurrent stroke risk by 39% in people who had a brain bleed.
Questions about Post-stroke depression
What are the benefits of acupuncture plus wet cupping for post-stroke depression?
A 2026 trial found that adding wet cupping to acupuncture led to greater improvements in depression scores and stroke recovery compared to acupuncture alone for mild-to-moderate post-stroke depression.
Full answer →How do various exercise therapies help patients with post-stroke depression?
Various exercise therapies like aerobic exercise, Tai Chi, and yoga reduce depressive symptoms in post-stroke depression, with home-based options also showing promise.
Full answer →