Living with functional neurological disorder (FND) can be incredibly frustrating. It affects how the body moves and functions, sometimes causing symptoms like motor issues or dissociative seizures. Because these symptoms are complex, finding the right treatment is a major challenge for patients and doctors alike.
A review of existing reports shows that ketamine or esketamine may lead to improvements in several areas. These include motor symptoms, dissociative seizures, and other functional presentations. While these results are encouraging, the evidence comes mostly from small cases and reports rather than large, controlled studies. This means the data is currently limited and varied.
Safety is a key consideration. While some side effects were reported, they were generally short-lived when given in a supervised clinic. However, because the current evidence is not yet strong enough to prove exactly how well the drug works, more large-scale trials are needed to see if the improvements are caused directly by the medication or other factors.