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Exercise Eases Anxiety and Depression in Postmenopausal WomenMind Body Training Shows Promise for Postmenopausal Anxiety and Depression

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Key Takeaway
Exercise, especially mind-body training, may reduce anxiety and depressive symptoms in postmenopausal women, with moderate doses being optimal.

A network meta-analysis examined the effects of exercise on anxiety and depressive symptoms in postmenopausal women. The analysis included 2,298 participants across multiple trials comparing exercise modalities—aerobic training, mind-body training, and combined aerobic and resistance training—against control conditions.

Overall, exercise interventions were associated with greater improvements in both anxiety and depressive symptoms compared to controls. Among the modalities, mind-body training showed the highest probability of benefit for both outcomes.

The study also explored the dose-response relationship between weekly exercise dose (MET-min/week) and symptom improvement. The associations were nonlinear, with moderate exercise doses generally yielding more favorable effects than very high doses.

However, the certainty of evidence was limited, and dose estimates were model-derived, so the findings should be interpreted cautiously. The results suggest that exercise, particularly mind-body training, may be a valuable non-pharmacological approach to support mental health in this population.

How this fits prior evidence

This finding addresses a gap in non-pharmacological management for mood symptoms in postmenopausal women. While previous coverage noted that Ashwagandha root extract is well-tolerated for stress and anxiety, and identified specific psychological factors like PTSD and trauma linked to worse outcomes in conditions like urinary incontinence, this study provides evidence on the efficacy of physical exercise modalities. It specifically highlights mind-body training as a promising intervention for anxiety and depression.

Researchers looked at how different types of exercise affect anxiety and depression in postmenopausal women. The study included over 2,000 women to compare aerobic training, mind body training, and a combination of aerobic and resistance training against no exercise.

The results showed that all forms of exercise generally led to better outcomes than doing nothing at all. Specifically, mind body training was linked to the highest probability of improving symptoms for both anxiety and depression. However, it is important to note that the evidence for these specific comparisons was limited.

Regarding how much exercise is needed, the study found a complex relationship between dose and results. The most favorable improvements were often seen at moderate weekly doses rather than very high amounts of exercise. Because some data were based on models rather than direct measurements, these findings should be viewed as an initial guide for potential benefits.

What this means for you:
Mind body training may help reduce anxiety and depression in postmenopausal women, especially at moderate doses.

Common questions

What types of exercise were studied for anxiety and depression?

The study looked at three main types: aerobic training, mind body training, and a combination of aerobic and resistance training. All of these exercise methods were found to be more effective than no exercise at all for managing symptoms in postmenopausal women.

Is mind body training better than other exercises?

The study showed that mind body training had the highest probability of benefit for both anxiety and depression. However, researchers noted that some of these specific comparisons were based on limited evidence, so it is a promising but still developing area.

How much exercise do postmenopausal women need to see results?

The study found a nonlinear relationship between the amount of exercise and the benefits. Generally, more favorable results were seen at moderate weekly doses rather than very high amounts of exercise. You should talk to your doctor about the best routine for you.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedAug 2026
View Original Abstract ↓
ObjectiveThis study aimed to compare the effects of different exercise modalities and explore the dose-response relationship between weekly exercise dose and symptoms of anxiety and depression in postmenopausal women.MethodsThis review included 23 randomized controlled trials involving 2,298 postmenopausal women. The main modality-level quantitative analyses included 17 studies for anxiety and 19 studies for depression, and were conducted using network meta-analysis (NMA) combined with Bayesian model-based dose-response analysis. Change-from-baseline standardized mean differences were used as effect measures. Exercise dose was standardized as weekly metabolic equivalent of task minutes (MET-min/week). Exercise interventions were classified as aerobic training (AT), mind-body training (FT), and combined aerobic and resistance training (AT+RT) for the main modality-level analyses. Resistance training (RT) was represented by only one study and was therefore not included in the main NMA or in ranking by the surface under the cumulative ranking curve (SUCRA).ResultsExercise interventions were generally associated with greater improvements in anxiety and depressive symptoms than control conditions. In the modality-level ranking, mind-body training showed the highest probability of benefit for both outcomes, although some comparisons were supported by limited evidence. Dose-response analyses suggested nonlinear associations, with more favorable model-derived effects generally observed at moderate weekly exercise doses rather than at very high doses.ConclusionExercise may help reduce anxiety and depressive symptoms in postmenopausal women, and mind-body training appears to be a promising modality. However, these findings should be interpreted cautiously because evidence certainty was limited and the dose estimates were model-derived.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD420251243356.
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