Triple therapy with TACE, TKIs, and ICIs shows survival benefits in unresectable hepatocellular carcinoma.
Triple therapy offers a 52% chance of living three years with advanced liver cancer.
This retrospective cohort study evaluated 270 patients with unresectable hepatocellular carcinoma receiving first-line triple therapy across…
Patients with advanced liver cancer receiving triple therapy had a 52% chance of surviving three years, offering new hope for those facing d…
Systematic review of anti-IL-5 biologics in hypereosinophilic syndrome kidney disease reports low certainty evidence.
New Clues Help Doctors Spot Kidney Trouble in Rare Blood Disease
This systematic review with narrative synthesis evaluates anti-IL-5 and IL-5Rα biologics in patients with histologically confirmed hypereosi…
A new review shows kidney issues in rare blood disorders are tricky to diagnose but may respond well to specific drugs.
Case Report Describes Treatment of Severe Mosquito Bite Allergy and EBV-Associated NK-Cell Lymphoproliferative Disorder
Why a 70-Year-Old Man’s Mosquito Bites Turned Deadly
This case report details the clinical management of a 70-year-old male with severe mosquito bite allergy and EBV-associated NK-cell lymphopr…
A single mosquito bite can sometimes signal a hidden immune problem, especially in older adults.
Narrative review explores TLR7 and TLR9 signaling networks within systemic lupus erythematosus and Sjögren's disease contexts.
Why Lupus and Sjögren’s Flares May Start in Your Cells’ “Mailroom”
This narrative review examines the role of TLR7 and TLR9 signaling networks in systemic lupus erythematosus and Sjögren's disease. The autho…
Understanding how these immune sensors misfire could lead to more precise treatments that calm flares without shutting down your whole immun…
Anti-CENP-B Antibody Positivity Associated With Clinical Features in Primary Sjögren’s Disease Cohort
Sjögren’s Disease: This Antibody Points to Milder Symptoms
This ambispective cohort study of 1,222 patients with primary Sjögren’s disease evaluated anti-CENP-B antibody positivity and associated cli…
Finding a specific antibody in your blood might mean your Sjögren’s disease is less active than expected.
Good's syndrome patients show reduced IgG, absent B cells, and altered Tfh subsets compared to healthy controls.
Why Your Immune System Stops Making Antibodies
This cohort study evaluated three patients with Good's syndrome and twenty healthy controls. Serum IgG levels were markedly reduced in all p…
Imagine your body as a fortress under constant attack.
Moxibustion plus montelukast for cough variant asthma with wind cold
Moxibustion plus montelukast improves cough-variant asthma symptoms and lung function
In 94 patients with cough variant asthma of wind cold attacking the lung, a randomized controlled trial compared modified painless wheat-gra…
Adding a painless moxibustion technique to montelukast improved symptoms, lung function, and long-term control in cough-variant asthma tied …
Review of remote ischemic conditioning for ischemic stroke highlights mechanistic targets and clinical variability.
A Simple Arm Squeeze Could Help Protect the Brain After Stroke
This narrative review examines remote ischemic conditioning (RIC) for ischemic stroke, synthesizing evidence on neuroprotective mechanisms a…
A simple arm cuffing method shows promise for protecting the brain, but timing is everything.
Bibliometric analysis maps multi-omics research growth in systemic autoimmune rheumatic diseases
How Scientists Are Finally Mapping the Hidden Triggers of Autoimmune Disease
This systematic bibliometric review analyzed 2,576 documents on multi-omics in systemic autoimmune rheumatic diseases. It reports a sharp ri…
We're entering a new era where doctors can hunt for the causes of autoimmune disease at the single-cell level, moving us closer to personali…
Narrative mini-review discusses mechanisms driving coronary atherosclerosis in patients with systemic lupus erythematosus
Why Lupus Can Speed Up Heart Disease, Even in Young People
This narrative mini-review synthesizes mechanistic insights regarding the link between systemic lupus erythematosus and coronary atheroscler…
Understanding how lupus harms blood vessels could help prevent heart attacks in people who don’t look high-risk.
Review Examines IL-32 Role in Cardiovascular Diseases and Atherosclerosis
New Blood Test Could Predict Heart Disease Risk Years Earlier
This review evaluates the role of IL-32 across cardiovascular diseases, atherosclerosis, myocardial infarction, and heart failure. However, …
This research could change how doctors spot heart disease risk, giving patients more time to prevent it.
Review summarizes therapeutic strategies targeting cGAS-STING-macrophage axis for renal fibrosis and chronic kidney disease.
New Kidney Damage Pathway Discovered—And Scientists Are Already Blocking It
This narrative review examines emerging therapeutic strategies targeting the cGAS-STING-macrophage axis for renal fibrosis and chronic kidne…
This research reveals a new way to stop kidney damage before it leads to failure.