Autoantibody positivity and false-negative cytology can mask invasive mucinous adenocarcinoma in patients with IPAF
Lung cancer can mimic autoimmune lung disease in some patients
This case report describes a 78-year-old female with invasive mucinous adenocarcinoma and interstitial pneumonia with autoimmune features. T…
A new case shows how a rare lung cancer can look like an autoimmune disease, making it hard for doctors to tell them apart.
Several risk factors including early-life antibiotic use and maternal OCP exposure increase allergic rhinitis risk
Several Risk Factors Linked to Children with Allergic Rhinitis
This umbrella review of systematic reviews and meta-analyses synthesizes evidence regarding 75 risk factors for pediatric allergic rhinitis.…
New research identifies various factors, like early-life antibiotic use and air pollution, that are linked to a higher risk of allergic rhin…
Structured clinical data models show moderate discrimination for predicting relapsing multiple sclerosis outcomes
New Models Show Potential for Predicting Multiple Sclerosis Relapses
This systematic review evaluates models for predicting relapse-related outcomes in patients with relapsing multiple sclerosis. Models based …
New models using clinical data show promise in predicting multiple sclerosis relapses, though more consistent testing is needed for daily us…
HLA-B alleles B*39:01, B*13:01, and B*38:02 serve as markers for sulfasalazine-induced SCARs in Asian populations
Genetic markers help predict severe reactions to sulfasalazine medication
This meta-analysis of a multicountry genetic study identifies specific HLA-B alleles as markers for sulfasalazine-induced severe cutaneous a…
New research identifies specific genetic markers that can help predict if patients with arthritis will have a severe skin reaction to sulfas…
Tumor immune microenvironment heterogeneity between thyroid and colorectal cancer drives distinct immune evasion mechanisms
Thyroid and colorectal cancers differ in immune environment
This systematic review compares the tumor immune microenvironment (TIME) in thyroid cancer and colorectal cancer. The authors find marked he…
Thyroid and colorectal cancers show distinct immune microenvironments, which may affect how they respond to immunotherapy.
Perioperative and postoperative immunotherapy timing determines clinical outcomes in locally advanced head and neck squamous cell carcinoma
Timing of immunotherapy affects outcomes for head and neck cancer
This narrative review examines the impact of immunotherapy sequencing on patients with locally advanced head and neck squamous cell carcinom…
The timing of immunotherapy treatment significantly changes how well it controls local and distant spread in head and neck cancer.
Comprehensive-component subcutaneous immunotherapy shows the most favorable symptom score reduction in allergic rhinitis
Comprehensive Immunotherapy Shows Best Results for Allergic Rhinitis Symptoms
This network meta-analysis of 7,329 participants evaluated three types of house dust mite allergen immunotherapy for allergic rhinitis. CC-S…
A large review of over 7,000 patients suggests that comprehensive subcutaneous immunotherapy may offer the strongest relief for allergic rhi…
Erythrocytes function as immunomodulatory participants and potential drivers of pathology in post-traumatic environments
Red blood cells play a key role in trauma recovery
This narrative review explores the role of erythrocytes in trauma, highlighting their immunomodulatory functions and potential to drive path…
Red blood cells do more than carry oxygen; they may actively help manage inflammation and tissue repair after a physical injury.
Allogeneic hematopoietic stem cell transplantation provides salvage for refractory chronic immune thrombocytopenia in a child
Stem Cell Transplant Shows Potential for Refractory Immune Thrombocytopenia
This case report with literature review describes a 6-year-old child with refractory chronic immune thrombocytopenia who achieved complete r…
A stem cell transplant provided a path to remission for a child with a severe form of immune thrombocytopenia.
Vunakizumab may induce severe ulcerative colitis and hepatic enzyme elevation in patients with psoriatic arthritis
Vunakizumab Linked to Severe Ulcerative Colitis in Single Case
This case report and literature review describes a single case of severe ulcerative colitis and hepatic enzyme elevation following vunakizum…
A single case report shows a patient developed severe ulcerative colitis and high liver enzymes after receiving vunakizumab injections.
Digital assessment modalities show feasibility and reliability in Myasthenia Gravis but lack independent validation
Digital tools show promise for tracking Myasthenia Gravis symptoms
This guideline provides a narrative review of digital assessment modalities for Myasthenia Gravis. Most studies demonstrate feasibility, adh…
New digital tools like wearable sensors and smartphone tasks could help track Myasthenia Gravis symptoms more closely during remote care.
DNA vaccines against MCPyV LTAg and STAg show potential for Merkel cell carcinoma immunotherapy
DNA Vaccines Show Promise Against Merkel Cell Carcinoma in Mice
This guideline summarizes preclinical data regarding DNA vaccines for Merkel cell carcinoma. The findings indicate that LTAgvax and STAgvax …
New DNA vaccines may help trigger a stronger immune response and slow tumor growth in models of Merkel cell carcinoma.