FDA Approves Adrenalin (epinephrine) for Anaphylaxis and Septic Shock Hypotension
FDA approves Adrenalin for severe allergic reactions and septic shock.
The FDA approved Adrenalin (epinephrine) for emergency treatment of allergic reactions including anaphylaxis, and to increase mean arterial …
The FDA approved Adrenalin (epinephrine) to treat life-threatening allergic reactions and low blood pressure from septic shock. It is given …
Point-of-care smell testing serves as an effective screening tool for various neurodegenerative and respiratory conditions
Point of Care Smell Testing Helps Identify Clinical Needs
This narrative review synthesizes the clinical utility of point-of-care olfactory tests across neurology, primary care, and otorhinolaryngol…
New research highlights how quick smell tests can serve as effective screening tools for patients with respiratory, neurological, and psychi…
Nanomedicine delivery systems may enhance immunotherapy efficacy in colorectal cancer
Nanomedicine may boost immunotherapy for colorectal cancer
This systematic review explores how nanomedicine delivery systems (liposomes, polymeric nanoparticles, metal nanoparticles) can remodel the …
Tiny particles could help immune therapies work better against colorectal cancer by changing the tumor environment.
Systemic Immune-Inflammation Index Shows Diagnostic and Prognostic Value in Thyroid Cancer
Immune Index Shows Link to Lymph Node Spread in Thyroid Cancer
A meta-analysis evaluated the Systemic Immune-Inflammation Index (SII) for diagnosing thyroid cancer and predicting lymph node metastasis. S…
A new analysis suggests that a specific immune marker could help doctors identify thyroid cancer and predict if it has spread to lymph nodes…
Small PNH clones in SLE linked to thrombotic events and hemolysis in case series
Small blood cell issues can impact patients with lupus and PNH
A systematic review of 8 cases found that 37.5% of SLE patients with PNH had thrombotic events and 87.5% had detectable hemolysis. The findi…
A review of cases shows that even small clusters of abnormal cells can cause serious blood complications in people with lupus and PNH.
Residual (meth)acrylate monomers trigger type IV hypersensitivity in dental settings
Dental materials may cause skin and tissue reactions in patients
This narrative review synthesizes evidence on (meth)acrylate monomers as haptens causing type IV hypersensitivity in patients and dental pro…
Residual chemicals in dental materials can trigger delayed allergic reactions in both patients and dental professionals.
NLRP3 inflammasome modulates immune evasion and chemotherapy sensitivity in gynecological cancers
New research identifies a key driver in gynecological cancer cells
This mini-review examines the role of the NLRP3 inflammasome in ovarian, endometrial, and cervical cancers. It highlights how NLRP3 impacts …
A protein called NLRP3 helps certain cancers hide from the immune system, but it also plays a complex role in how tumors react to treatment.
The osteoimmune-brain axis links systemic inflammation and bone hormones to neurodegenerative pathology
Immune system may link bone health and brain disease
This systematic review examines the role of the osteoimmune-brain axis, where the immune system mediates skeletal and cerebral pathology thr…
A new look at the body's immune system suggests a link between bone health and conditions like Alzheimer's and dementia.
Ferroptosis contributes to endothelial dysfunction, macrophage foam cell death, and necrotic core expansion in atherosclerosis
Ferroptosis May Drive Damage in Arterial Atherosclerosis
This systematic review synthesizes the role of ferroptosis in arterial atherosclerosis by examining iron homeostasis, lipid metabolism, and …
New research identifies how a specific type of cell death called ferroptosis may contribute to the growth of plaque and damage in blood vess…
Metabolic reprogramming of lipid-associated macrophages creates an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
Specific immune cells help pancreatic cancer grow and spread
This narrative review characterizes the role of lipid-associated macrophages (LAMs) and their metabolic pathways in the pancreatic ductal ad…
Researchers identified how specific fat-loving immune cells create a shield that protects pancreatic tumors from the body's natural defenses…
Phenotype-weighted and organ-prioritized frameworks should guide treatment for autoinflammatory diseases despite molecular diagnosis limitations
Molecular diagnosis alone may not guide autoinflammatory disease treatment
This narrative review examines the management of autoinflammatory diseases, including type I interferonopathies and inflammasome-related dis…
A new review finds that knowing the genetic cause of an autoinflammatory disease often doesn't predict which organs will be affected or how …
Immune-mediated loss of HCRT neurons drives sleep-wake circuit instability and brain network reconfiguration in narcolepsy
New research explains how immune attacks cause narcolepsy symptoms
This systematic review synthesizes the pathophysiology of narcolepsy, focusing on how genetic and environmental factors trigger an immune-me…
A new look at narcolepsy reveals how an immune-driven attack on specific brain cells causes sleep issues and sudden muscle weakness.