Network meta-analysis compares osteoporosis drugs for bone density in men
Men's Osteoporosis Drugs Work Better on Spines Than Hips
This network meta-analysis of 4,409 men with primary osteoporosis compared six medications. It found significant improvements in bone minera…
• Abaloparatide and teriparatide boost spine bone density most • Helps men with weak bones avoid fractures • Not yet proven to prevent actua…
Narrative review on managing hypertriglyceridemia in pregnancy, including olezarsen and volanesorsen
High Triglycerides In Pregnancy Need New Safe Drug Options Soon
This narrative review synthesizes evidence on hypertriglyceridemia in pregnancy. It covers lifestyle and pharmacologic options, noting trigl…
Pregnant women with very high triglycerides face dangerous risks but safe new drugs are not yet approved for use during delivery.
Meta-analysis reports elevated IL-6 and IL-17 in thyroid eye disease patients
New Clues in Your Tears Could Change Thyroid Eye Disease Care
This meta-analysis of observational studies found that serum or tear levels of IL-6 and IL-17 were significantly higher in patients with thy…
Two inflammatory markers found in blood and tears are significantly higher in people with thyroid eye disease, offering new clues for faster…
Secondary analysis of HIV trial links hematologic factors to neurocognitive disorder risk in substance users
HIV Brain Fog Tied to Blood Levels and Daily Habits
This secondary analysis of a randomized clinical trial evaluated 801 people with HIV who use substances across 11 U.S. hospitals. The study …
Lower hemoglobin and recent alcohol use raise brain fog risk in people with HIV who use substances.
Systematic review of saponins for type 2 diabetes and its complications
Saponins Show New Promise for Type 2 Diabetes and Complications
This systematic review summarizes the antidiabetic effects of saponins in type 2 diabetes. Saponins modulate key signaling pathways and show…
New research shows plant compounds called saponins may help manage type 2 diabetes and protect organs from related damage.
Systematic review links psycho-emotional and environmental factors to eating behaviors in adults with overweight or obesity
Young adults eat to cope with stress, not just hunger
This systematic review synthesizes evidence from 7,614 participants regarding factors associated with eating behaviors in young and middle-a…
Doctors now know that stress and emotions drive eating habits in young adults, so treating the mind helps manage weight.
Narrative review examines voltage-dependent K+ channels in rodent and human studies
New Potassium Channels Could Change How We Treat Diabetes
This narrative review synthesizes findings from rodent and human studies regarding voltage-dependent K+ channels. The authors discuss the sc…
Tiny potassium channels in the pancreas act like gatekeepers for insulin, and scientists now think targeting them could lead to smarter diab…
FDA Approves Levothyroxine Sodium Tablets for Hypothyroidism and TSH Suppression
FDA approves new thyroid hormone drug for hypothyroidism and thyroid cancer.
The FDA approved levothyroxine sodium tablets for replacement therapy in primary, secondary, and tertiary hypothyroidism, and as an adjunct …
The FDA has approved levothyroxine sodium tablets to treat hypothyroidism and as part of therapy for certain thyroid cancers. This synthetic…
Stand-alone digital lifestyle interventions show significant improvements in weight and dietary habits for adults with overweight or obesity compared to controls
Digital Tools Help Adults Lose Weight Without Human Support
A systematic review and meta-analysis of 19 studies involving 3,556 adults found that stand-alone digital lifestyle interventions significan…
New research shows that fully automated digital tools can help adults lose weight and eat better without needing a human coach or live suppo…
Pregabalin 300 or 600 mg/day significantly reduces pain in painful diabetic peripheral neuropathy versus placebo
Higher doses of pregabalin helped reduce pain scores for people with painful diabetic nerve problems compared to placebo
This randomized controlled trial enrolled 729 patients with painful diabetic peripheral neuropathy. Pregabalin doses of 300 mg/day and 600 m…
A study found that taking 300 or 600 mg of pregabalin daily lowered pain scores better than a fake pill. Lower doses did not work as well fo…
Network Meta-Analysis Finds Tirzepatide and Sleeve Gastrectomy Equally Effective for Weight Loss in Obesity
New Weight Loss Pill Matches Surgery Results Without the Scalpel
A network meta-analysis of 14,293 adults with obesity found that tirzepatide 10 or 15 mg and sleeve gastrectomy achieved similar weight loss…
A diabetes drug now pulls even with stomach surgery for weight loss offering hope to millions who dread going under the knife but it is not …
Digital Health Interventions Show Mixed Results for Cardiovascular Risk Reduction in Type 2 Diabetes Patients Across Weight Categories
Digital Health Tools Help Some Diabetes Patients But Not Others
A secondary analysis of the SMARTDiabetes trial reveals that digital health interventions failed to lower 10-year cardiovascular risk in the…
Digital health tools cut heart risk for people with diabetes who have normal weight, but not for those who are overweight or obese.