Case report describes secukinumab use in a woman with erythrodermic psoriasis and systemic capillary leak syndrome
One case report links secukinumab to severe capillary leak syndrome in a woman with psoriasis
This case report details the clinical course of a 66-year-old woman with new-onset erythrodermic psoriasis who developed systemic capillary …
A woman with psoriasis developed life-threatening capillary leak syndrome after starting secukinumab, with symptoms improving only after sto…
TyG-GGT index predicts incident diabetes mellitus in a 5-year retrospective cohort of 8,678 screened participants.
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This retrospective cohort study of 8,678 participants undergoing health screenings at Kuichong People's Hospital in Shenzhen evaluated the T…
A new blood score combining fat and sugar data predicts diabetes risk better than standard tests used today.
Retrospective cohort study assesses diagnostic accuracy for Wagner Grade ≥2 DFUs in hospitalized type 2 diabetes patients.
New Tool Predicts Severe Foot Ulcers in Diabetic Patients Before They Worsen
This retrospective cohort study evaluated diagnostic accuracy for Wagner Grade ≥2 diabetic foot ulcers (DFUs) in 510 hospitalized patients w…
This new calculator could help doctors spot dangerous foot ulcers in diabetic patients sooner, giving them a chance to act before it’s too l…
Untargeted LC-MS/MS profiling identifies metabolite networks associated with glycemic dysregulation in diabetes cohorts.
A new chemical link connects early diabetes risks to specific proteins in your blood.
This cohort study profiled 15,470 serum metabolite features in people with normal glucose tolerance, prediabetes, and type 2 diabetes. Coreg…
Scientists found a specific chemical pattern that grows stronger as diabetes gets worse, offering a fresh view on how the disease starts.
Laboratory study examines SLC30A8 R138X variant effects on human stem cell-derived islet-like clusters.
How a Genetic Mutation Shields Pancreas Cells From Stress
This research article reports a laboratory study investigating the SLC30A8 R138X loss-of-function variant in human stem cell-derived islet-l…
A specific gene mutation acts as a natural shield, keeping insulin-producing cells alive when they face zinc stress that usually causes them…
Endocrinologist-led glucose management with RT-CGM and insulin infusion improved glycemic control and reduced infections in adult EICU patients.
ICU Blood Sugar Control Gets a Game-Changing Upgrade
This retrospective before-after study evaluated 1138 adult EICU patients with stays ≥24 hours. The endocrinologist-led glucose management (E…
A new ICU blood sugar control method slashes dangerous highs and infections while keeping critically ill patients safer.
Narrative review discusses osteoclast-osteoblast coupling mechanisms and therapeutic strategies for skeletal diseases.
Bone Health May Depend on a Hidden Cellular Conversation
This narrative review examines the complex communication between osteoclasts and osteoblasts, noting that the molecular logic governing this…
Understanding how bone cells talk to each other could lead to smarter treatments that build bone without breaking it down.
Meta-analysis finds preadmission metformin use associated with reduced mortality in diabetic sepsis patients
Metformin Linked to Lower Sepsis Death Risk
This systematic review and meta-analysis of 14 studies (12,687 patients) examined preadmission metformin use in diabetic sepsis patients. It…
Diabetic patients taking metformin before sepsis face nearly 40% lower death risk, suggesting this common pill may quietly boost survival du…
Young-onset type 2 diabetes and menopause status linked to all-cause mortality in Chinese women.
Diabetes at 40? This Number Could Save Your Life
This observational cohort study of 5984 Chinese women with type 2 diabetes found a lower all-cause mortality rate in young-onset versus late…
For postmenopausal women under 40 with diabetes, a specific marker predicts higher death risk than age alone, offering a vital early warning…
Systematic review on subclinical ketosis mechanisms and diagnostics in dairy cows
Why is a hidden illness hurting dairy cows after birth?
This systematic review synthesizes evidence on endocrine–metabolic mechanisms, diagnostic strategies, and economic consequences of subclinic…
A hidden metabolic problem hits dairy cows right after birth, impairing their immune system, reducing milk yield, and increasing risks for p…
Progressive high-risk biological aging linked to increased urolithiasis risk in Chinese cohort.
Your Aging Pattern Could Predict Kidney Stones
This observational cohort study of 27,948 participants found that a Progressive High-Risk biological aging trajectory was associated with an…
How fast your body ages, not just your calendar age, may be a hidden driver of painful kidney stones.
Machine learning model using 32 variables predicts osteoporotic fractures in postmenopausal women
Machine learning model may help predict fracture risk in postmenopausal women
This retrospective cohort study of 1717 postmenopausal women in China evaluated a machine learning model for osteoporotic fracture predictio…
A new tool uses blood tests and bone density to predict fracture risk in postmenopausal women with high accuracy.