Total testosterone and BMI predict clomiphene citrate resistance in 6.8% of women with PCOS
High Testosterone and BMI Predict Clomiphene Resistance in PCOS
This post-hoc analysis of a multicenter randomized controlled trial involving 471 infertile women with polycystic ovary syndrome (PCOS) iden…
New analysis shows that high testosterone levels and higher body mass index can help predict if clomiphene citrate will work for women with …
Combined exercise interventions significantly reduce glycated hemoglobin and fasting blood glucose in type 2 diabetes
Combined exercise shows better results for type 2 diabetes
This meta-analysis of 1401 patients with type 2 diabetes evaluates the impact of exercise on glucose metabolism and body composition. The an…
Combining different types of exercise can lower blood sugar and improve body composition more than aerobic exercise alone for people with ty…
Quantitative pancreatic MRI shows promise as non-invasive biomarker in diabetes
MRI Imaging Shows Promise for Early Diabetes Diagnosis
This literature review examines quantitative pancreatic MRI as a potential non-invasive biomarker for diabetes. The authors find it holds pr…
New imaging techniques using MRI may offer a non-invasive way to detect diabetes early and monitor how well treatments are working over time…
General medical management improves medication adherence and lifestyle outcomes in older adults with type 2 diabetes
New management model improves medication use and health for seniors
This randomized controlled trial of 200 older adults with type 2 diabetes and atherosclerotic cardiovascular disease found that a general me…
A new personalized care plan helps older adults with diabetes and heart disease stay on their medications and improve their daily habits.
Apoptotic regulation and multi-hit factors drive germ cell loss in non-obstructive azoospermia
Apoptosis in Non-Obstructive Azoospermia: A Multi-Hit Model
This narrative review examines the role of apoptotic pathways and a multi-hit model in non-obstructive azoospermia. The authors suggest that…
This review explores how programmed cell death (apoptosis) contributes to non-obstructive azoospermia, highlighting a multi-hit model where …
Surgery remains the only curative treatment for primary hyperparathyroidism, review confirms
Surgery Remains the Only Cure for Hyperparathyroidism
This narrative review on hyperparathyroidism confirms that surgery is the only curative treatment for primary HPT. The field has shifted fro…
A new review confirms surgery is the only cure for hyperparathyroidism, with minimally invasive techniques now standard.
IL-6 blockade causes early lipid increases but maintains cardiovascular neutrality in rheumatoid arthritis
New review clarifies how IL-6 blockers affect cholesterol in arthritis
This narrative review examines the impact of IL-6 inhibitors tocilizumab and sarilumab on lipid profiles and cardiovascular outcomes in pati…
Doctors are looking closer at why some rheumatoid arthritis medications cause early spikes in cholesterol levels and what that means for hea…
Preoperative androgen therapy reduces odds of urethrocutaneous fistula in pediatric hypospadias repair
Androgen therapy may reduce complications in hypospadias surgery
This network meta-analysis of 715 patients evaluated preoperative hormone therapies for hypospadias. The analysis found that androgen therap…
New data suggests that androgen hormone therapy can lower the risk of specific complications after hypospadias repair for pediatric patients…
Hyperuricemia affects 22% of type 2 diabetes patients in global meta-analysis
Type 2 Diabetes Linked to Higher Risk of Gout
This meta-analysis of 977,573 patients with type 2 diabetes found a pooled hyperuricemia prevalence of 22.0% and gout prevalence of 6.0%. Ri…
A large analysis shows that many people with type 2 diabetes also have high uric acid levels and a higher risk of developing gout.
TTM-based interventions significantly reduce BMI and waist circumference in individuals with overweight or obesity
TTM Based Interventions Show Potential for Weight Loss
This meta-analysis of 20 studies involving 1,736 participants found that Transtheoretical model (TTM)-based interventions led to significant…
A review of 20 studies shows that TTM based programs may help people with overweight or obesity reduce their BMI and waist size.
Post-translational modifications represent a critical target for precise molecular intervention in diabetic kidney disease
Protein modifications may drive diabetic kidney disease progression
This systematic review examines the role of post-translational modifications (PTMs) such as phosphorylation and acetylation in diabetic kidn…
A new review reveals how tiny protein changes fuel diabetic kidney disease, opening doors for targeted treatments.
Selpercatinib tops cabozantinib and vandetanib for PFS in advanced medullary thyroid cancer
Selpercatinib Shows Better Survival for Advanced Medullary Thyroid Cancer
A network meta-analysis of 1,076 patients with advanced medullary thyroid cancer found selpercatinib superior to cabozantinib and vandetanib…
A new analysis of 1,076 patients suggests selpercatinib may offer better progression-free survival than other treatments for medullary thyro…