Network Meta-Analysis Finds Tirzepatide and Semaglutide Most Effective for Weight Loss in Adults
New Weight Loss Drugs Protect Your Heart and Lower Death Risk
A systematic review and network meta-analysis of 63,909 adults found that all obesity medications produced greater weight loss than placebo.
New data from 66 trials shows top obesity drugs significantly reduce heart events and death while helping with liver and joint pain issues f…
Semaglutide linked to lower neuropsychiatric event risk vs other diabetes drugs in observational study
Semaglutide linked to lower neuropsychiatric risk than other diabetes drugs
This observational cohort study analyzed 63,215 patients with baseline neuropsychiatric conditions across a large US federated data platform…
A large observational study suggests semaglutide may be associated with a lower risk of neuropsychiatric conditions compared to other common…
Meta-analysis of dapagliflozin for renal outcomes in type 2 diabetes and CKD
SGLT2 inhibitors lower kidney failure risk in type 2 diabetes patients
This systematic review and meta-analysis of 10 studies synthesized evidence on dapagliflozin for renal outcomes in patients with type 2 diab…
A review of ten studies shows these drugs reduce kidney failure risk in people with type 2 diabetes and kidney disease.
Protocol for culturally adapted cardiovascular dance intervention in Mapuche women with obesity and cardiometabolic disorders
Study protocol for dance intervention in Indigenous Chilean community
This study protocol describes a randomized controlled trial involving 22 Mapuche women with overweight, obesity, or cardiometabolic disorder…
A new study protocol plans to test culturally adapted dance versus traditional exercise for health in an Indigenous Chilean community.
Systematic review links diabetes to impaired immune control of tuberculosis pathogenesis across 81 studies
Diabetes changes how the body fights tuberculosis infection in humans and animals
This systematic review synthesizes evidence from 81 eligible studies involving animal models and human participants to examine how diabetes …
A review of 81 studies shows diabetes weakens the immune system, making tuberculosis worse and harder to control in people and lab animals.
Narrative review links microgravity exposure to altered fat distribution and inflammation in metabolic disease models
How Space Travel Is Unlocking New Ways to Fight Obesity and Diabetes
This narrative review synthesizes evidence from human studies, animal models, and in vitro experiments regarding microgravity and metabolic …
This research shows that the same health problems astronauts face in space are happening to people on Earth who sit too much, and it may lea…
Biochemical remission of Cushing's syndrome reduces hepatic steatosis and fibrosis indices in adult patients
Cushing’s Syndrome Often Leads to Fatty Liver Disease
This retrospective cohort study evaluated 126 adult patients with endogenous Cushing's syndrome (CS).
New findings reveal fatty liver is common in Cushing’s syndrome, yet liver fat may improve after treatment ends, offering hope for patients.
Combination valsartan and dapagliflozin improves blood pressure and glucose in Type 2 Diabetes and hypertension
Two Common Heart and Kidney Drugs Work Better Together Than Alone
This retrospective cohort study of 245 patients with coexisting Type 2 Diabetes Mellitus and hypertension found that combination therapy wit…
For patients with diabetes and high blood pressure, combining two common medications may offer stronger protection for the heart and kidneys…
High 1-mg DST, low PNI, diabetes, and poor bone health predict infection in Cushing syndrome surgery
High Cortisol Levels Signal Higher Infection Risk Before Surgery
This retrospective single-center cohort study evaluated 113 patients with confirmed Cushing syndrome.
Doctors can now spot patients at high risk for surgery infections days before the operation starts.
CGM-Derived Glycemic Persistence Index Predicts OGTT 2-Hour Glucose in Dysglycemia
Wearable Glucose Monitor Could Replace Burdensome Blood Test
In an observational cohort of adults with paired free-living CGM and OGTT, the glycemic persistence index (GPI) was the strongest single pre…
A new way to read glucose monitor data might make testing easier.
MCH1 Receptor Antagonist RGH-706 Shows Weight Loss in Preclinical and Early Clinical Study
New Drug Targets Hunger Brain Signals to Help Shed Pounds
A preclinical and phase I/II study evaluated the MCH1 receptor antagonist RGH-706 for obesity and Prader-Willi Syndrome.
Scientists found a new medicine that may help people lose weight by turning off hunger signals.
Longitudinal ABCD Study links central fat dynamics to cognitive deficits in adolescents
How Fat Gain in Teens Changes the Brain’s Wiring
This longitudinal observational study from the Adolescent Brain Cognitive Development (ABCD) Study analyzed central fat dynamics in 8,519 ad…
Your teen’s brain is still building itself.