Meta-analysis finds high prevalence of adverse outcomes in African women with hyperglycaemia in pregnancy
High Sugar in Pregnancy Risks C-Section in Africa
A systematic review and meta-analysis of 9,742 women with hyperglycaemia in pregnancy in Africa found high prevalence rates of caesarean sec…
High blood sugar during pregnancy in Africa significantly raises the risk of needing a C-section, threatening both mother and baby.
Orforglipron shows superior HbA1c reduction versus oral semaglutide in adults with type 2 diabetes on metformin
A New Diabetes Pill Takes On Ozempic's Oral Cousin
A phase 3 RCT of 1698 adults with type 2 diabetes inadequately controlled on metformin found that once-daily oral orforglipron (12 mg or 36 …
A new once-daily diabetes pill called orforglipron lowered blood sugar better than oral semaglutide in a major head-to-head trial, but at th…
L-citrulline with HIIT alters specific microRNAs in obese older adults
How 12 Weeks of Hard Exercise Changes the Molecular Machinery of Aging Muscle
A secondary exploratory analysis of a double-blind randomized trial in 68 obese older adults found that 12-week HIIT with L-citrulline suppl…
A 12-week high-intensity interval training program produced measurable molecular changes in older adults' muscles — and a natural supplement…
Single aerobic exercise bout shows mixed effects on glucose and neuronal insulin signaling in obesity
A Single Workout That Talks to Your Brain
A small RCT in 15 sedentary adults with obesity found a single bout of aerobic exercise at 70% VO₂max showed a trend toward lower glucose AU…
One workout session raised insulin signals in brain particles, offering a clue to how exercise may protect against Alzheimer's over time.
Anakinra reduces inflammatory markers in prediabetes but shows no metabolic improvements in RCT
Two anakinra injections changed blood markers in people with prediabetes
A randomized controlled trial in individuals with prediabetes found that two injections of anakinra significantly reduced total leucocyte co…
Two anakinra injections quickly lowered inflammation markers in people with prediabetes, though the drug did not yet improve blood sugar con…
Sugammadex improves diaphragmatic excursion and reduces pulmonary complications in morbidly obese patients
Sugammadex Helps Obese Patients Breathe Easier
A randomized double-blind controlled trial in 104 morbidly obese patients compared sugammadex (2 mg/kg) with neostigmine+atropine. Sugammade…
This new research shows that a specific reversal drug helps morbidly obese patients breathe better and avoid lung issues after surgery.
Circulating spexin levels are significantly lower in patients with type 2 diabetes mellitus compared to controls.
The Hormone That Goes Missing When Diabetes Arrives
This systematic review and meta-analysis evaluated circulating spexin levels in 1,122 patients with type 2 diabetes mellitus and 681 control…
A little-known hormone called spexin shows up in much smaller amounts in people with type 2 diabetes, hinting at a possible link scientists …
Risk factors for recurrence in patients undergoing percutaneous endoscopic lumbar discectomy for lumbar disc herniation
Back Surgery Worked — So Why Did the Disc Come Back?
This systematic review and meta-analysis evaluated 14,454 patients undergoing percutaneous endoscopic lumbar discectomy (PELD) for lumbar di…
A large analysis of nearly 15,000 patients identifies who is most likely to need repeat back surgery — and what lifestyle factors make recur…
Cultural dietary patterns linked to lower obesity risk in global meta-analysis
Your Food Habits Are Shaping Your Weight Risk
A meta-analysis of 48 studies across 68 countries found that traditional dietary patterns were associated with a 23% lower obesity risk and …
Sticking to traditional diets lowers obesity risk by 23% compared to Westernized eating, while moving away from home culture raises it.
Gut microbiome dysbiosis and dietary modifications are associated with Polycystic Ovary Syndrome in women of reproductive age.
Your Gut Microbiome May Be Playing a Hidden Role in PCOS
This systematic review examined the role of gut microbiome dysbiosis, dietary modifications, and probiotic supplementation in women of repro…
A comprehensive review finds that disruptions in gut bacteria may fuel the hormonal chaos, insulin resistance, and inflammation at the heart…
Meta-analysis links BMI to breast cancer subtype risk with menopausal status differences
Does Weight Change Breast Cancer Risk? It Depends on When
A systematic review and meta-analysis of 2,103,181 pre- and post-menopausal women found BMI associations with breast cancer subtype risk var…
Extra weight raises breast cancer risk after menopause, but before menopause it's linked to more aggressive tumor types, a review of over 2 …
PRP infusion improves pregnancy rates in recurrent implantation failure but may increase preterm births
Platelet Plasma Boosts Pregnancy in Repeat Failures
A meta-analysis in women with recurrent implantation failure found that intrauterine autologous platelet-rich plasma (PRP) infusion signific…
Platelet-rich plasma triples pregnancy rates for women with recurrent implantation failure, but it also raises the risk of preterm birth.