TyG indices associated with coronary artery disease risk in first-time angiography patients
Your Blood Sugar and Fat Levels Together May Signal Heart Attack Risk
This retrospective cohort study evaluated 3,641 patients undergoing initial coronary angiography to assess the association between Triglycer…
Two routine blood test numbers, combined into one simple calculation, may give doctors a clearer early warning sign for heart disease than e…
TyG and TyHGB indices predict type 2 diabetes onset in elderly Chinese cohort
Two Simple Blood Tests Predict Diabetes Risk Better Than BMI
A prospective cohort study of 18,251 community-dwelling elderly individuals in Shenzhen, China, found that six obesity- and lipid-related in…
Two calculated scores using routine blood test values may identify older adults heading toward diabetes years before standard screening catc…
Hair cortisol concentration correlates with glucocorticoid adequacy and symptoms in adults with adrenal insufficiency.
Your Hair Holds a Hidden Record of a Dangerous Hormone Imbalance
This cross-sectional study evaluated hair cortisol concentration (HCC) in 64 adults with hydrocortisone-treated adrenal insufficiency compar…
A strand of hair can reveal months of hormone history, helping fine-tune treatment for adrenal insufficiency to avoid dangerous over- or und…
PIEZO1 variant rs563555492T associated with lower HbA1c and reduced prediabetes risk in South Asian cohorts.
A Hidden Gene Is Masking Diabetes in South Asians
This observational cohort study examined 62,909 South Asians from India and the UK to assess the impact of the PIEZO1 rs563555492T variant. …
A gene common in South Asians can make standard diabetes blood tests look normal even when blood sugar is high, hiding the disease for years…
Semaglutide dose linked to lower mortality and cardiovascular risk in patients with baseline CVD
Why Ozempic's Heart Benefits May Have Nothing to Do With Weight Loss
An observational study of 47,199 patients with baseline cardiovascular disease in a U.S. EHR network found higher maximum semaglutide dose w…
A massive real-world study of over 47,000 heart patients suggests that semaglutide may protect the heart through direct biological effects —…
Cross-sectional review of top 100 endocrinology journals reveals varying AI usage policies in Instructions for Authors.
AI Rules Are Missing in Top Endocrinology Journals
This cross-sectional review analyzed AI usage policies in the Instructions for Authors of the top 100 endocrinology journals. Results indica…
Most top endocrinology journals let researchers use AI to write papers and create images, yet almost none require specific reporting guideli…
Single-dose fultagliptin benzoate pharmacokinetics and safety in patients with mild to moderate renal insufficiency versus healthy volunteers
A New Diabetes Pill That Stays Longer When Kidneys Slow
This Phase I, non-randomized, open-label, parallel-control trial evaluated the pharmacokinetics, pharmacodynamics, and safety of a single or…
A new diabetes pill builds up in the body when kidneys slow, meaning some patients with mild or moderate kidney issues may need half the usu…
In older in-patients with type 2 diabetes and cognitive impairment, CGM showed superior glucose metrics compared to point-of-care tests.
The Wearable Glucose Sensor That Catches What Hospital Tests Miss
This observational study evaluated continuous glucose monitoring (CGM) versus point-of-care tests (POCT) in 30 older in-patients with type 2…
A new wearable sensor caught dangerous overnight low blood sugar in older hospitalized patients with dementia that routine hospital tests co…
Exercise training improves function in 157 patients with mitochondrial myopathy
Exercise May Strengthen Muscles Doctors Once Told to Rest
This meta-analysis and systematic review evaluated moderate-intensity aerobic and resistance exercise in 157 patients with mitochondrial myo…
For a disease once treated with rest, a careful exercise plan now looks like one of the most promising tools to rebuild strength.
Scoping review of molecular pathways in insulin resistance among women with PCOS
Your PCOS Symptoms May Start in Your Cells, Not Your Weight
This scoping review examined molecular or cellular pathways related to insulin resistance or glucose metabolism in women of reproductive age…
Women with PCOS often face insulin resistance rooted in cells, not weight, shifting treatment focus from body size to cellular signals for b…
Systematic review links gut microbiota dysbiosis to CKD-MBD, RA, OA, and OP pathogenesis.
Your gut holds the key to your bone health.
This systematic review examines the role of gut microbiota dysbiosis in chronic kidney disease-mineral and bone disorder (CKD-MBD), rheumato…
Gut bacteria directly influence bone strength and kidney health, yet current treatments ignore the digestive system where the real problem s…
Autologous cell therapy improved healing rates and reduced ulcer area in patients with diabetic foot ulcers compared to control.
Using your own cells to heal stubborn diabetic foot wounds
This meta-analysis and systematic review evaluated autologous cell therapy versus control in 2,214 patients with diabetic foot ulcers. The a…
Using a patient's own cells to jump-start healing may close diabetic foot ulcers that regular treatment leaves open for months.