Myo-inositol and clomiphene with sildenafil are associated with improved pregnancy outcomes in women with infertility
New findings show specific treatments may improve fertility outcomes
This meta-analysis evaluates various interventions for infertility, including hormonal therapies, ART strategies, and investigational adjunc…
Certain supplements and stress management programs show promise for women struggling with infertility, though more data is needed on safety.
Metformin is associated with higher lactate concentrations during exercise in adults with prediabetes and type 2 diabetes
Metformin May Raise Lactate During Exercise
This meta-analysis of 325 participants evaluated the impact of metformin on exercise metabolism and capacity. The analysis found that metfor…
A new analysis suggests metformin may increase lactate levels during exercise, which could affect workout intensity.
Semaglutide reduces risk of kidney decline or death in type 2 diabetes and CKD
Semaglutide lowers kidney and heart risks in type 2 diabetes patients
This randomized controlled trial enrolled 3,533 participants with type 2 diabetes and chronic kidney disease. Once-weekly subcutaneous semag…
A large trial shows once-weekly semaglutide reduces kidney failure and death risks in people with type 2 diabetes and chronic kidney disease…
Stress-induced IL-6 upregulation impairs skeletal growth and bone health in children with inflammatory diseases
Stress hormones may harm bone growth in children with inflammatory conditions
This narrative review synthesizes evidence from animal models and pediatric inflammatory disorders showing that stress-induced IL-6 upregula…
A review suggests stress-induced IL-6 upregulation impairs skeletal growth and bone health in kids with inflammatory disorders, highlighting…
MTARC1 inhibition may reduce cirrhosis and hepatocellular carcinoma risk in metabolic dysfunction-associated steatotic liver disease
Blocking a liver protein could lower risks for fatty liver disease patients
This meta-analysis of data from the Quebec Obesity Biobank used integrated proteogenomic analysis and Mendelian randomization to assess caus…
A massive analysis suggests blocking a specific liver protein might reduce risks for fatty liver disease, cirrhosis, and cancer while improv…
Early genomic profiling optimizes treatment selection and expands precision therapy options across thyroid cancer subtypes
Targeted therapies expand options for advanced thyroid cancer
This narrative review discusses molecular profiling and targeted therapies for patients with advanced, recurrent, or radioiodine-refractory …
New review shows molecular profiling can unlock more personalized treatments for people with advanced thyroid cancer.
Oral white kidney bean extract reduces weight by 1.62 kg in adults with overweight or obesity compared to placebo
White kidney bean extract helps adults with overweight lose weight in this review
This systematic review and meta-analysis evaluated oral white kidney bean extract for weight management in adults with overweight or obesity…
A review of 543 adults found that taking white kidney bean extract led to weight loss and reduced body fat compared to a placebo.
IGFBPs show dual roles in metabolic dysfunction-associated steatotic liver disease progression
IGFBP proteins play opposite roles in liver disease progression
This narrative review synthesizes evidence on insulin-like growth factor-binding proteins (IGFBPs) in metabolic dysfunction-associated steat…
A review shows specific IGFBP proteins can protect the liver or drive damage depending on the stage of disease and which protein is involved…
Type 5 diabetes in low-income populations with early malnutrition is underdiagnosed and needs standardized care
Type 5 Diabetes: A Hidden Threat in Poorer Nations
This narrative review examines Type 5 diabetes mellitus in low-income populations with early-life malnutrition. It finds the condition is un…
A new review reveals Type 5 diabetes, linked to early malnutrition, is often missed in low-income regions.
FDA Approves Saxenda (liraglutide) for Weight Management in Adults and Adolescents
FDA approves Saxenda for weight management in adults and teens.
The FDA approved Saxenda (liraglutide) for chronic weight management in adults with obesity or overweight with comorbidities, and in pediatr…
The FDA approved Saxenda (liraglutide) for chronic weight management in adults with obesity or overweight plus a weight-related condition, a…
FDA Approves Brenzavvy (bexagliflozin) for Type 2 Diabetes Glycemic Control
FDA approves Brenzavvy, a new pill for type 2 diabetes.
The FDA approved Brenzavvy (bexagliflozin), an SGLT2 inhibitor, as an adjunct to diet and exercise to improve glycemic control in adults wit…
The FDA approved Brenzavvy (bexagliflozin) to help lower blood sugar in adults with type 2 diabetes. It is taken once a day with or without …
FDA Approves Farxiga (dapagliflozin) for Chronic Kidney Disease and Heart Failure
FDA approves Farxiga for chronic kidney disease and heart failure.
FDA approved Farxiga (dapagliflozin) to reduce risk of eGFR decline, end-stage kidney disease, cardiovascular death, and heart failure hospi…
The FDA approved Farxiga to treat chronic kidney disease and heart failure in adults. It helps protect the kidneys and heart, even in people…