Metabolic subtypes identify Japanese adults with prediabetes at highest or lowest T2D risk
Japanese adults with prediabetes benefit most from lifestyle changes in one specific metabolic group
This randomized controlled trial enrolled 295 Japanese adults with impaired glucose tolerance in the Japanese Diabetes Prevention Program. P…
A study of 295 Japanese adults found that lifestyle changes work best for those with a specific metabolic pattern. This group had the lowest…
Network meta-analysis reveals optimal aerobic exercise frequency and intensity for improving bone mineral density in osteoporosis patients
Network meta-analysis finds aerobic exercise improves bone density in osteoporosis patients
A comprehensive network meta-analysis of 2,183 participants demonstrates that aerobic exercise significantly boosts bone mineral density acr…
A network meta-analysis of 2,183 participants shows aerobic exercise improves bone density better than control, with specific intensity and …
Pantoprazole exposure linked to insulin autoimmune syndrome in case report
Stopping a stomach acid drug helped a patient with low blood sugar recover
This case report describes a patient with insulin autoimmune syndrome (IAS) temporally associated with pantoprazole exposure. Discontinuatio…
A patient with insulin autoimmune syndrome found relief when doctors stopped a common stomach acid medication, suggesting a possible link be…
Processing methods for ovarian tissue in healthy premenopausal patients were reviewed with no reported outcomes or safety data
Review of methods for handling ovarian tissue from healthy patients
This review examines various processing methods for ovarian tissue collected from healthy premenopausal patients in operating room or transp…
A review looked at ways to process ovarian tissue from healthy women. It found that how the tissue is handled can affect its quality for res…
37 loci linked to gestational diabetes, 7 novel, in large multi-ancestry meta-analysis
Scientists found new genetic links to diabetes during pregnancy in this large study
This meta-analysis of genome-wide association studies across up to 38,305 GDM cases and 776,145 controls identified 37 loci associated with …
A massive study looked at DNA from many people to find genes linked to diabetes in pregnancy. They discovered new genetic markers that help …
FDA Approves Afrezza (insulin human) Inhaled Insulin for Adult Diabetes
FDA approves Afrezza, an inhaled insulin for adults with diabetes.
FDA approved Afrezza, a rapid-acting inhaled human insulin, to improve glycemic control in adults with diabetes. It is administered at the b…
The FDA approved Afrezza, an inhaled insulin powder for adults with diabetes. It is taken at the start of meals using a special inhaler, off…
Ring-augmented gastric bypass shows similar weight loss and safety at one year
Ring-augmented gastric bypass shows similar weight loss at one year
This single-center RCT compared ring-augmented one-anastomosis gastric bypass to conventional bypass in 214 adults. At one year, weight loss…
Adding a silicone ring to gastric bypass didn't improve weight loss or safety at one year in a small trial.
GLP-1RAs show lower risk of serious liver events compared with DPP-4 inhibitors in adults with type 2 diabetes
GLP-1 drugs may lower serious liver risks compared to DPP-4 inhibitors in type 2 diabetes
This systematic review and exploratory meta-analysis evaluated incident cirrhosis or composite serious liver events among adults with type 2…
A new analysis suggests GLP-1 receptor agonists might reduce serious liver events compared to DPP-4 inhibitors for adults with type 2 diabet…
Novel NBAS variants define severe immune dysregulation and poor prognosis in infantile liver failure syndrome type 2
A Chinese girl reveals new genetic causes for severe infant liver failure and immune problems
This case report with systematic review examines NBAS-related disease across 322 previously reported patients. The authors identify novel co…
New genetic findings explain severe liver failure and immune issues in infants, offering hope for earlier diagnosis and care.
Anti-inflammatory reliever therapy outperforms SABA-only in asthma management
Doctors suggest using anti-inflammatory reliever therapy for better asthma control and safety
This narrative review compares anti-inflammatory reliever (AIR) therapy and SMART/MART with SABA-only bronchodilators for asthma. The author…
This review looks at asthma treatments. Using anti-inflammatory reliever therapy may help people breathe easier and stay safe compared to us…
Thiazolidinediones show lower hepatocellular carcinoma risk than DPP-4 inhibitors, GLP-1RAs, insulin, and sulfonylureas in this network meta-analysis
New analysis links diabetes drugs to liver outcomes in millions of patients
This network meta-analysis evaluated major adverse liver outcomes among 7124845 adults with type 2 diabetes using glucose-lowering drug clas…
A massive analysis of millions of patients found some diabetes medications linked to lower risks of serious liver events compared to others.
GLP-1 receptor agonists reduce major adverse limb events with HR 0.59 in PAD
New analysis shows GLP-1 drugs cut stroke risk for people with leg artery disease
This systematic review and meta-analysis of over 240,000 adults with peripheral artery disease found that GLP-1 receptor agonists significan…
A large review of real-world data found GLP-1 drugs significantly reduce stroke and heart attack risk in adults with peripheral artery disea…