Narrative review on BAT in older adults with obesity and exercise nutrition
Researchers find exercise and nutrition linked to fat burning in older adults with obesity
This narrative review synthesizes evidence on brown adipose tissue in older adults with obesity. It finds BAT volume and activity are reduce…
A review links exercise and nutrition to reduced fat-burning capacity in older adults with obesity, raising questions about how to support m…
CGM may boost treatment satisfaction in type 2 diabetes, but other outcomes unclear
CGM May Boost Treatment Satisfaction in Type 2 Diabetes
A meta-analysis finds CGM may improve treatment satisfaction over self-monitoring in type 2 diabetes, but effects on distress, well-being, a…
Continuous glucose monitoring may improve treatment satisfaction for people with type 2 diabetes, but effects on distress and well-being are…
Systematic review and meta-analysis of prediction models for diabetic kidney disease progression to ESRD
Kidney disease prediction models show promise but have major flaws
This meta-analysis of 15 studies evaluated prediction models for diabetic kidney disease progression to end-stage renal disease. Pooled AUCs…
Models that predict kidney failure in diabetic patients look accurate, but studies have serious problems that limit their use in real clinic…
Systematic review explores metabolic-immune axis in glioma progression and resistance
Metabolic-immune link in glioma opens new treatment avenues
This systematic review synthesizes evidence on the metabolic-immune interplay in glioma. It finds that metabolic reprogramming and immune mi…
A systematic review reveals how metabolic reprogramming and immune evasion work together in glioma, pointing to new targets for therapy.
Meta-analysis suggests high BMI causally increases vascular-related dementia risk via blood pressure mediation
Higher body weight linked to increased risk of vascular dementia
This Mendelian randomization meta-analysis evaluates the causal link between high body mass index and vascular-related dementia. The analysi…
A large genetic study shows that a higher body mass index (BMI) raises the risk of vascular-related dementia. High blood pressure plays a ke…
Systematic review and meta-analysis of metformin for pediatric overweight and obesity shows modest BMI reduction
Metformin shows promise for weight management in children with overweight or obesity
This systematic review and meta-analysis evaluated metformin versus placebo in children with overweight or obesity across 19 original studie…
A meta-analysis of 19 studies suggests metformin may help lower BMI and weight in children with overweight or obesity compared to placebo.
Systematic review and meta-analysis on FGF23 levels in diabetic kidney disease
High FGF23 levels are linked to diabetic kidney disease in this new analysis
This systematic review and meta-analysis synthesized data from 3,799 participants on the association between FGF23 levels and diabetic kidne…
A large review found that people with diabetic kidney disease have much higher FGF23 levels than those without the condition.
Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
Adding homocysteine screening helps spot dangerous pregnancy complications earlier
This narrative review evaluates homocysteine combined with multi-index screening for detecting preeclampsia, fetal growth restriction, gesta…
A review suggests adding homocysteine checks to standard tests helps doctors spot risks like preeclampsia and fetal growth restriction more …
CagriSema demonstrates superior weight loss efficacy compared to semaglutide monotherapy or placebo in obesity trials
New drug combo beats standard treatment for obesity and heart risks
A systematic review and meta-analysis of 4,419 patients reveals CagriSema drives greater weight loss than semaglutide alone. However, clinic…
This new drug combination helps people lose more weight and lowers blood pressure, but it causes more stomach upset that needs careful watch…
Systematic review finds no difference in hypoglycemia or ketoacidosis between insulin types
Children on insulin may not need newer expensive versions
A meta-analysis of 1,107 children with type 1 diabetes found no significant difference in severe hypoglycemia, ketoacidosis, or serious adve…
A major review finds older human insulin works as safely as newer analogues for children with type 1 diabetes, which could ease costs for fa…
Meta-analysis: Resistance training improves vascular function in type 2 diabetes
Resistance Training Improves Blood Vessel Health in Type 2 Diabetes
This meta-analysis of RCTs examined effects of resistance training (RT) alone or combined with aerobic training on vascular function in adul…
A review of 20 studies found that resistance training, especially with aerobic exercise, improves artery flexibility and blood vessel functi…
Scoping review synthesizes functional factors for enhancing physical strength and endurance
7 Supplements That Boost Strength and Endurance Naturally
This scoping review synthesizes evidence on functional factors for enhancing physical strength and endurance. It lists specific nutritional …
Forget one-size-fits-all supplements: new research shows that strength athletes and endurance athletes need completely different nutrients t…