Tirzepatide MTD Demonstrates Cost-Effectiveness Versus Semaglutide MTD in Obesity Simulation Modeling Study
Tirzepatide Saves Money and Health Over Semaglutide
This simulation modeling study using Phase-3 trial data evaluated tirzepatide versus semaglutide in individuals with obesity or overweight w…
Imagine standing in a doctor's office, facing a choice between two powerful weight-loss medicines.
Network meta-analysis on stem cell therapy for osteonecrosis of the femoral head
Higher Dose of Own Stem Cells May Protect Hip Bones Better Than Standard Surgery
This systematic review and network meta-analysis synthesized evidence from 18 studies involving 1,192 patients with osteonecrosis of the fem…
For patients with a collapsing hip bone, adding a high dose of their own stem cells to a common surgery may delay or prevent the need for a …
Meta-analysis of adjunctive SGLT2 inhibitors in type 1 diabetes shows mixed safety and efficacy signals
No More Bone Fear With New Diabetes Drug
This meta-analysis evaluated adjunctive SGLT2 inhibitor therapy in 6,731 patients with type 1 diabetes mellitus receiving insulin-based ther…
Many people with type 1 diabetes worry about their bones.
Secukinumab 300 mg subcutaneously failed to demonstrate overall response in adults with active Graves orbitopathy versus placebo
Secukinumab showed no benefit for active Graves orbitopathy patients
This randomized, double-blind, placebo-controlled trial evaluated secukinumab versus placebo in 28 adults with active, moderate-to-severe…
Secukinumab treatment for Graves orbitopathy showed no improvement in symptoms or eye measurements compared to placebo treatment.
Antiresorptive and Anabolic Agents Improve Bone Microarchitecture in Postmenopausal Women With Type 2 Diabetes: Pilot RCT
Diabetes Weakens Bones: One Drug Builds Them Back
This pilot randomized controlled trial evaluated antiresorptive and anabolic agents in 129 postmenopausal women with Type 2 Diabetes.
Building new bone tissue with a specific daily shot works better than just protecting existing bone for women with diabetes.
Systematic review and meta-analysis on LH-active gonadotropins for ovarian stimulation in infertility
Adding LH-active hormone to fertility treatment doesn't boost live births
This meta-analysis of 56 RCTs with 14,034 women found little to no difference in live birth or ongoing pregnancy when adding LH-active gonad…
For women using fertility drugs, adding LH doesn't improve live birth or pregnancy odds, but it may slightly lower egg yield without raising…
Systematic review and meta-analysis of integrative therapies for Type 1 Diabetes Mellitus
Yoga and Natural Therapies Help Control Type 1 Diabetes
This meta-analysis of 12 studies on integrative therapies for Type 1 Diabetes Mellitus found adjunctive benefits for glycemic control.
It’s 6 a.m. and 12-year-old Maya stirs awake.
Meta-analysis of observational studies associates serum lipid levels with diabetic nephropathy risk
High Triglycerides Raise Risk of Kidney Damage in Diabetes
This meta-analysis synthesizes data from 15 observational studies examining serum lipid levels and diabetic nephropathy risk.
Managing blood fats might help protect your kidneys if you have diabetes.
Meta-analysis links higher FT3 and TgAb to permanent hypothyroidism after subacute thyroiditis
After Thyroid Inflammation, Some Patients Face Lifelong Hormone Issues—New Clues Explain Why
This systematic review and meta-analysis of 1294 patients with subacute thyroiditis found that higher free triiodothyronine (FT3) levels and…
This research helps doctors predict which patients will need lifelong thyroid medication after inflammation, allowing for earlier monitoring…
Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
Kidney Damage May Start With Fat in the Wrong Places
This systematic review summarizes mechanisms and therapeutic strategies targeting renal ELD across kidney diseases, including diabetic and…
This research explains how fat in the wrong kidney cells causes harm, opening new paths for prevention and treatment.
Meals4Moms intervention for gestational diabetes shows feasibility in pilot RCT
Delivered Meals Could Help Pregnant Moms Control Blood Sugar
This pilot randomized controlled trial assessed a medically-tailored meal delivery and education intervention for pregnant individuals with …
A new program delivering healthy food and exercise tips shows promise for managing blood sugar during pregnancy.
Systematic review links mitochondrial dysfunction to idiopathic inflammatory myopathies
Muscle Weakness May Start in Your Cells' Power Plants, Not Inflammation
This systematic review synthesizes evidence on immunometabolic dysregulation in idiopathic inflammatory myopathies.
Your muscle weakness might be a fuel problem, not just an inflammation problem.