Impact of Antidiabetic Medications on Survival Outcomes in Patients with Cancer
Metformin use linked to lower death rates in cancer patients
A large-scale meta-analysis reveals significant differences in mortality risks between metformin, insulin, and SGLT2 inhibitors in cancer pa…
A large study of over one million patients suggests that the common diabetes drug metformin may help lower mortality rates for those with ca…
Orforglipron demonstrates an acceptable safety profile in Japanese adults with type 2 diabetes over 52 weeks
Trial shows safety of oral orforglipron for type 2 diabetes
This Phase 3 randomized controlled trial evaluated the safety of orforglipron in 401 Japanese adults with type 2 diabetes over 52 weeks. The…
A new trial shows that the daily oral medication orforglipron was well tolerated by adults with type 2 diabetes over a one-year period.
Bariatric surgery linked to wider retinal arterioles and narrower venules in obesity
Bariatric Surgery Linked to Improved Retinal Blood Vessel Health
This meta-analysis of prospective cohort studies examined retinal microvascular calibre after bariatric surgery in patients with obesity. Po…
Bariatric surgery may improve blood vessel measurements in the eyes for people with obesity, potentially impacting long-term eye health.
MACS affects 26.2% of primary aldosteronism patients and tracks with higher cardiometabolic odds
Mild Cortisol Secretion Linked to Heart Risks in Aldosteronism
This meta-analysis of 2356 patients with primary aldosteronism estimates a pooled MACS prevalence of 26.2% (95% CI 24.1-28.4). MACS co-occur…
Patients with primary aldosteronism and mild cortisol secretion may face higher risks of heart issues and type 2 diabetes.
Serum folate concentrations do not differ significantly in patients with various thyroid disorders
Comparing Folate Levels in People with Different Types of Thyroid Disorders
This meta-analysis of 5492 participants found no significant differences in serum folate concentrations between adults with hypothyroidism, …
A large study looked at folate levels in people with thyroid issues. The results showed no major differences compared to healthy people.
Adjunctive placental-derived CAMPs raise 12-week diabetic foot ulcer closure versus standard care
Placental Products May Help Heal Diabetic Foot Ulcers
This meta-analysis of 944 adults with active diabetic foot ulcers found that adjunctive placental-derived cellular, acellular, and matrix-li…
New research suggests that adding placental-derived products to standard care can increase the chances of closing diabetic foot ulcers withi…
Impact of GLP-1 Receptor Agonists on Body Composition and Bone Health in Obesity
GLP-1 Medications Linked to Lower Lean Body Mass in Patients
A meta-analysis of over 1.2 million patients reveals GLP-1 receptor agonists significantly reduce fat-free mass during weight loss.
New data shows that GLP-1 medications for type 2 diabetes and obesity are linked to a decrease in lean body mass.
Digital health interventions reduce HbA1c by 0.37 percentage points in adults with type 2 diabetes
Digital Health Tools Show Modest Progress for Type 2 Diabetes
This meta-analysis of randomized controlled trials found that digital health interventions (DHIs) led to a modest but statistically signific…
Digital health tools can help people with type 2 diabetes lower their HbA1c levels, especially for those in underserved communities.
Tirzepatide ranks highest for weight and waist reduction among GLP-1 and GLP-1/GIP receptor agonists
Tirzepatide and Semaglutide Show Significant Weight Loss for Obesity
This systematic review and network meta-analysis of randomized controlled trials evaluates liraglutide, semaglutide, and tirzepatide for wei…
New analysis shows tirzepatide and semaglutide effectively reduce body weight and BMI for adults with obesity or being overweight.
Semaglutide is not associated with significantly increased risks of depression, anxiety, or suicidal ideation
Semaglutide Shows No Significant Link to Increased Depression Risk
This meta-analysis evaluated the psychiatric safety of semaglutide in patients with Type 2 Diabetes and Obesity. The analysis found no stati…
New data suggests that semaglutide does not significantly increase risks of depression, anxiety, or suicidal ideation in patients with type …
Resistance exercise maintains significant net reduction in T2D risk at 1 year
Resistance exercise may help prevent type 2 diabetes risk rebound
This randomized controlled trial of 221 sedentary women with overweight found that resistance exercise maintained a significant net reductio…
A new trial shows that adding resistance exercise to a weight loss diet may help women maintain lower risks for type 2 diabetes.
Near-infrared autofluorescence did not significantly improve cure rates in parathyroidectomy for primary hyperparathyroidism
Glowing Technique Falls Short in Parathyroid Surgery
This meta-analysis of 3 studies involving 522 patients evaluated near-infrared autofluorescence (NIRAF) compared to visual identification du…
A special light meant to help surgeons see parathyroid glands better didn't improve cure rates or surgery time in a new analysis.