Network meta-analysis reveals placenta-derived products significantly improve diabetic foot ulcer healing rates versus standard care options
New topical treatments show strong promise for healing diabetic foot ulcers
A comprehensive network meta-analysis of 6,161 patients demonstrates that twelve topical therapies enhance wound healing in diabetic foot ul…
A major analysis of 6,161 patients found that 12 topical therapies significantly improved wound healing rates compared to standard care for …
Scoping review of micronutrient intake in midlife women across six Asian regions
Micronutrient gaps in Asian midlife women may harm bone health and daily life
This scoping review synthesized evidence on micronutrient intake and status among midlife women in six Asian regions. It found suboptimal in…
A review of eight publications shows that low intake of vitamins and minerals is linked to worse bone health and lower quality of life for w…
Meta-analysis finds higher intrapancreatic fat in type 2 diabetes
People with Type 2 Diabetes have significantly higher fat inside their pancreas
This systematic review and meta-analysis of 3980 individuals found that intrapancreatic fat deposition (IPFD) measured by MRI is significant…
A large review found that people with Type 2 Diabetes have much more fat stored inside their pancreas compared to healthy people.
Systematic review and meta-analysis links COVID-19 infection to 41% higher new-onset diabetes risk
Meta-analysis links COVID-19 infection to higher new-onset diabetes risk
This systematic review and meta-analysis evaluated sixteen studies comparing COVID-19 survivors with non-infected individuals. The pooled an…
A meta-analysis of sixteen studies suggests COVID-19 infection is associated with a 41% increased risk of developing new-onset diabetes at l…
Narrative review on BAT in older adults with obesity and exercise nutrition
Researchers find exercise and nutrition linked to fat burning in older adults with obesity
This narrative review synthesizes evidence on brown adipose tissue in older adults with obesity. It finds BAT volume and activity are reduce…
A review links exercise and nutrition to reduced fat-burning capacity in older adults with obesity, raising questions about how to support m…
CGM may boost treatment satisfaction in type 2 diabetes, but other outcomes unclear
CGM May Boost Treatment Satisfaction in Type 2 Diabetes
A meta-analysis finds CGM may improve treatment satisfaction over self-monitoring in type 2 diabetes, but effects on distress, well-being, a…
Continuous glucose monitoring may improve treatment satisfaction for people with type 2 diabetes, but effects on distress and well-being are…
Systematic review and meta-analysis of prediction models for diabetic kidney disease progression to ESRD
Kidney disease prediction models show promise but have major flaws
This meta-analysis of 15 studies evaluated prediction models for diabetic kidney disease progression to end-stage renal disease. Pooled AUCs…
Models that predict kidney failure in diabetic patients look accurate, but studies have serious problems that limit their use in real clinic…
Systematic review explores metabolic-immune axis in glioma progression and resistance
Metabolic-immune link in glioma opens new treatment avenues
This systematic review synthesizes evidence on the metabolic-immune interplay in glioma. It finds that metabolic reprogramming and immune mi…
A systematic review reveals how metabolic reprogramming and immune evasion work together in glioma, pointing to new targets for therapy.
Meta-analysis suggests high BMI causally increases vascular-related dementia risk via blood pressure mediation
Higher body weight linked to increased risk of vascular dementia
This Mendelian randomization meta-analysis evaluates the causal link between high body mass index and vascular-related dementia. The analysi…
A large genetic study shows that a higher body mass index (BMI) raises the risk of vascular-related dementia. High blood pressure plays a ke…
Systematic review and meta-analysis of metformin for pediatric overweight and obesity shows modest BMI reduction
Metformin shows promise for weight management in children with overweight or obesity
This systematic review and meta-analysis evaluated metformin versus placebo in children with overweight or obesity across 19 original studie…
A meta-analysis of 19 studies suggests metformin may help lower BMI and weight in children with overweight or obesity compared to placebo.
Systematic review and meta-analysis on FGF23 levels in diabetic kidney disease
High FGF23 levels are linked to diabetic kidney disease in this new analysis
This systematic review and meta-analysis synthesized data from 3,799 participants on the association between FGF23 levels and diabetic kidne…
A large review found that people with diabetic kidney disease have much higher FGF23 levels than those without the condition.
Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
Adding homocysteine screening helps spot dangerous pregnancy complications earlier
This narrative review evaluates homocysteine combined with multi-index screening for detecting preeclampsia, fetal growth restriction, gesta…
A review suggests adding homocysteine checks to standard tests helps doctors spot risks like preeclampsia and fetal growth restriction more …