GLP-1 RAs and dual incretin agonists cause delayed gastric emptying and lean mass loss in patients
New guidelines for patients using weight loss drugs before surgery
This mini-review examines the impact of GLP-1 RAs and dual incretin agonists on patients undergoing aesthetic surgery. The review highlights…
Patients using weight loss drugs like GLP-1 RAs may face specific risks like delayed stomach emptying before undergoing aesthetic surgery.
INSL3 serves as a robust alternative to testosterone or LH for reflecting Leydig cell status
New protein marker may help track male fertility and health
This narrative review explores the role of INSL3 in male reproductive health and its potential as a biomarker for Leydig cell status. The au…
A protein called INSL3 could offer a more reliable way to track male reproductive health and cell function than current methods.
Structured educational and behavioral interventions reduce fear of hypoglycemia in adults with type 2 diabetes
Education and Behavior Programs May Reduce Fear of Low Blood Sugar
This meta-analysis of 1096 adults with type 2 diabetes found that structured educational and behavioral interventions significantly reduced …
Structured educational and behavioral programs may help adults with type 2 diabetes feel less anxious about the risk of low blood sugar leve…
Resting energy expenditure does not meaningfully differ between women with and without PMOS
PCOS May Not Change Resting Energy Expenditure Much
This meta-analysis examined whether resting energy expenditure (REE) differs between women with and without polyendocrine metabolic ovarian …
Women with PMOS and those without burn almost the same calories at rest, a new analysis suggests.
Comparative Efficacy and Safety of Endoscopic Sleeve Gastroplasty Versus Laparoscopic Sleeve Gastrectomy
Sleeve gastrectomy leads to more weight loss than endoscopic procedure
A meta-analysis of 7,442 patients compares ESG and LSG, highlighting significant differences in weight loss and GERD risk.
A new review shows that while endoscopic sleeve gastrectomy is safer for some, traditional surgery leads to more weight loss.
CagriSema Combination Therapy Demonstrates Superior Weight Reduction Over Semaglutide Monotherapy
Combination drug shows greater weight loss than semaglutide alone
CagriSema provides significantly greater weight loss and BMI reduction compared to semaglutide 2.4 mg, with increased injection-site reactio…
A new drug combination helps people with weight and type 2 diabetes lose more weight than semaglutide alone, though it may cause more skin i…
Urinary incontinence is a prevalent and often undermanaged consequence of endometrial cancer and its treatments
Endometrial cancer treatments often lead to common urinary incontinence
This systematic review synthesizes evidence regarding the relationship between endometrial cancer and urinary incontinence. The review ident…
Women with endometrial cancer often face urinary incontinence after treatment, a common but often overlooked side effect that requires bette…
Microglia are currently candidate contributors rather than established clinical targets in polycystic ovary syndrome
Microglia May Play a Role in Polycystic Ovary Syndrome
This narrative review explores the role of microglia in polycystic ovary syndrome. The authors conclude that while microglia are potential c…
New research explores how brain cells called microglia might influence conditions like Polycystic Ovary Syndrome, though more human data is …
SGLT2 inhibitors improve glycemic control and blood pressure in patients with diabetic chronic kidney disease
SGLT2 inhibitors improve blood sugar and weight in kidney disease
This meta-analysis evaluated the effects of SGLT2 inhibitors on glycemic control, weight, and blood pressure in patients with diabetic chron…
SGLT2 inhibitors help manage blood sugar, weight, and blood pressure for people with diabetes and chronic kidney disease.
Patients with Graves' disease and Hashimoto's thyroiditis have significantly lower serum 25-hydroxyvitamin D levels
Thyroid Patients May Have Lower Vitamin D Levels
This meta-analysis of 38 studies found significantly lower serum vitamin D levels in patients with thyroid diseases compared to non-thyroid …
People with thyroid conditions, especially Hashimoto's, tend to have lower vitamin D levels, a new analysis finds.
IcoSema reduces HbA1c by 3.32 percentage points compared to 2.44 in type 2 diabetes
New weekly insulin combination shows better results for type 2 diabetes
This Phase 3b randomized trial of 485 adults with type 2 diabetes found that once-weekly IcoSema significantly reduced HbA1c by 3.32 percent…
A new once-weekly insulin combination helps people with type 2 diabetes lower their blood sugar and lose more weight.
Mongolian Medicine Compounds Show Immunomodulatory Potential in Sepsis, But Direct Evidence Remains Scarce
Traditional Mongolian Medicine shows potential for treating sepsis models
This narrative review examines Traditional Mongolian Medicine compounds (Daruqi particles, HHQG, Hohgardi-9, Nagab-9, Monflu, Batri-7, Qiqir…
Traditional Mongolian medicines like quercetin and berberine show potential to manage inflammation in sepsis models, though more human trial…