SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
New review shows SGLT2 drugs raise DKA risk when blood sugar is high
This meta-analysis of observational and randomized trials found SGLT2 inhibitor use is associated with an increased risk of diabetic ketoaci…
A big review of many studies found that medicines for diabetes called SGLT2 inhibitors can increase the chance of a serious condition called…
Early-life antibiotic exposure linked to modest increased risk of childhood type 1 diabetes
Meta-analysis links early-life antibiotic use to higher childhood type 1 diabetes risk
This meta-analysis of early-life antibiotic use found a modest increased risk of childhood type 1 diabetes. Prenatal exposure showed a poole…
A large meta-analysis suggests early antibiotic exposure may slightly raise childhood type 1 diabetes risk, though causality remains unclear…
Trans fatty acids from dairy foods show no increased cardiometabolic risk in systematic review and meta-analysis
Dairy fat with altered cow diets does not raise heart disease risk
This systematic review and meta-analysis of 10 RCTs and 12 prospective cohort studies found that trans fatty acids from dairy foods were not…
A large review of dairy foods shows that fat from cows with altered diets does not increase heart disease risk or diabetes risk.
Roots, leaves, and fruits of Himachal Pradesh herbs are traditionally used for diabetes management
Traditional plants from Himachal Pradesh show promise for diabetes
This narrative review examines traditional antidiabetic medicinal plants from Himachal Pradesh, India. The authors report that roots (17%), …
A review of 80 local herbs suggests they may help manage diabetes, though more research is needed to confirm their safety and effectiveness.
Adverse childhood experiences linked to higher gestational diabetes risk
Early life stress may raise risk of gestational diabetes in later pregnancy
A meta-analysis of observational studies examined whether adverse childhood experiences are associated with gestational diabetes mellitus. T…
A massive analysis of over 326,000 people found that childhood adversity is linked to higher odds of developing gestational diabetes during …
Paternal metformin use during spermatogenesis shows no increased risk for major congenital malformations in over 11 000 children across five countries
New analysis shows fathers taking metformin did not raise birth defect risks for their children
A large meta-analysis involving more than 11 000 live-born children found no association between fathers taking metformin and birth defects.…
A large study of over 11,000 children found no higher risk of birth defects when dads took metformin before conception. This good news appli…
Multicomponent behavioral interventions show sustained HbA1c reduction in type 2 diabetes
New analysis shows combining behavioral strategies helps adults with type 2 diabetes control blood sugar better over time
This network meta-analysis of behavioral interventions for adults with type 2 diabetes found that multicomponent strategies combining cognit…
A large review found that adding cognitive behavioral therapy and motivational interviewing to standard care lowers blood sugar more than st…
Triple oral therapy with metformin, SGLT-2, and DPP-4 inhibitors lowers HbA1c better than dual regimens in adults with type 2 diabetes
Triple oral diabetes drugs lower blood sugar better than two-drug regimens
A systematic review and meta-analysis of 2,606 adults with type 2 diabetes found that triple oral therapy combining metformin, an SGLT-2 inh…
A large analysis shows that taking three specific oral diabetes medicines together lowers blood sugar more effectively than taking just two …
Probiotics, synbiotics, and berberine modestly lower fasting glucose and HbA1c in type 2 diabetes
Probiotics and Berberine Modestly Lower Blood Sugar in Type 2 Diabetes
This meta-analysis of over 2,000 participants found that probiotics, synbiotics, and berberine produced significant but modest reductions in…
Probiotics, synbiotics, and berberine may help lower blood sugar and HbA1c, but the effects are modest.
Natural polysaccharides enhance insulin sensitivity and protect pancreatic beta-cells in type 2 diabetes
Natural polysaccharides may help manage Type 2 Diabetes through multiple biological pathways
This comprehensive review examines the mechanisms by which natural polysaccharides influence type 2 diabetes. The authors synthesize evidenc…
A comprehensive review suggests natural polysaccharides could improve insulin sensitivity and protect pancreatic cells in Type 2 Diabetes.
Women with Type 1 Diabetes have a 2.10 times higher risk of female sexual dysfunction compared to age-matched controls
Women with Type 1 Diabetes face a higher risk of sexual dysfunction than controls
This systematic review and meta-analysis evaluated the prevalence and risk of female sexual dysfunction in women with Type 1 Diabetes. The p…
A large review found that women with Type 1 Diabetes are significantly more likely to experience sexual dysfunction compared to healthy wome…
Cerivastatin best for total cholesterol, simvastatin for LDL-C in DKD with hyperlipidemia
Lipid-Lowering Drugs Show Different Benefits for Kidney Disease
A network meta-analysis of 20 RCTs in patients with diabetic kidney disease and hyperlipidemia found that cerivastatin most effectively redu…
A review of 20 trials found that different statins and fenofibrate have unique effects on cholesterol, kidney markers, and heart risks in di…