FirstCPR cluster randomised trial process evaluation finds leadership and champions drive community BLS uptake
Community groups in Australia showed high engagement with new life support training programs
A multimethod process evaluation of the FirstCPR cluster randomised trial examined delivery, reach, uptake and engagement of multimodal basi…
Social and faith-based groups in Australia successfully adopted new life support training, with 90% engaging in activities while only 18% co…
Corticosteroids reduce short-term and long-term mortality in adult sepsis patients according to a systematic review
What Doctors Give Sepsis Patients Is Finally Getting Clearer
This systematic review and network meta-analysis evaluated corticosteroids, specifically hydrocortisone and hydrocortisone plus fludrocortis…
Corticosteroids cut short-term and long-term sepsis death risk for ICU adults in large review, though doctors still need clearer guidance on…
Higher plasma potassium levels associate with increased 30-day mortality in ED patients
Even Mildly High Potassium Raises Death Risk
This retrospective cohort study analyzed 248,453 persons attending Emergency Departments in the Capital Region of Denmark from 2017 to 2021.
Doctors need to pay closer attention to even small rises in potassium because they signal a serious health warning.
Thiamin supplementation associated with reduced mortality in septic shock patients
Thiamin Cuts Death Risk in Sepsis Shock
This meta-analysis of randomized controlled trials evaluated thiamin supplementation versus placebo or blank controls in patients with septi…
A common vitamin called thiamin lowers death risk and kidney failure needs for patients in septic shock, offering new hope for severe infect…
Simplified ventilator built from automotive parts delivered tidal volumes up to 600 mL in severe lung disease models
Can a simple machine built from car parts keep patients breathing when power fails?
This preclinical study evaluated a simplified mechanical ventilator assembled from automotive components in simulated adult/pediatric patien…
A ventilator built from car parts successfully kept air moving and oxygen levels safe in emergency tests when standard hospital machines fai…
Immune dysregulation score predicts mortality and identifies hydrocortisone responders in community-acquired pneumonia
Three Blood Markers May Pick Who Benefits From Sepsis Steroids
A multicohort analysis and reanalysis of an RCT developed and validated an immune dysregulation score using three plasma biomarkers in 398 d…
A simple three-blood-test model may finally pick which sepsis patients benefit most from steroid treatment, using biology instead of guesswo…
A 1-hour sepsis bundle is associated with reduced short-term mortality compared to non-bundle care in a meta-analysis of 4435 patients
One Hour Saves Lives in Sepsis
This systematic review and meta-analysis evaluated the association between a 1-hour sepsis bundle and short-term mortality in 4435 patients …
A specific 1-hour checklist for treating sepsis significantly lowers short-term death rates compared to standard care, offering a simple way…
Neuropsychiatric documentation varies widely in adult ED patients with behavioral health complaints requiring clearance
What Gets Missed When ER Doctors Meet Mental Health Patients
This retrospective cohort study reviewed electronic medical records of 507 adult ED patients with behavioral health complaints requiring med…
At one urban ER, important pieces of the neurological and psychiatric exam were missing from records for many patients arriving in mental he…
Diaphragm ultrasound combined with D-RSBI predicts weaning outcomes in neurocritical patients on mechanical ventilation
An Ultrasound May Reveal When Patients Can Breathe Alone
This retrospective analysis examined 128 patients with severe neurological conditions on mechanical ventilation at a Chongqing neurosurgery …
A simple bedside ultrasound of the main breathing muscle, paired with a breath-counting ratio, helped doctors tell who was ready to breathe …
CytoSorb hemoadsorption shows no benefit and potential harm in small septic shock trial
A Promising Sepsis Treatment May Do More Harm Than Good
A single-center RCT of 31 adults with septic shock and high IL-6 found no significant difference in cumulative norepinephrine dose (primary …
A high-tech blood filter for sepsis failed to help patients and may have worsened early survival rates in a new study.
EMG provides diagnostic and therapeutic guidance for patients with cervical dystonia
EMG Helps Pinpoint Neck Pain Cause
This systematic review evaluated the clinical value of electromyography (EMG) in patients with cervical dystonia.
This simple test helps doctors stop painful neck spasms by finding the right muscles to treat.
Mini-review examines MRSA-influenza co-infection pathogenesis and adjunctive therapies
Flu Damage Lets Bacteria Destroy Your Lungs
A mini-review examines the pathogenesis of MRSA-influenza co-infection, noting influenza damages respiratory epithelium and facilitates S.
Flu damage breaks your lung's protective shield, letting bacteria multiply and destroy healthy tissue to cause severe pneumonia.