In adult ED encounters, clinician engagement with EHR-based SDOH data was rare but higher in opioid use disorder cases
Did reviewing social data in the ER actually change how doctors treated opioid use disorder patients?
This cross-sectional study of 17,103 adult emergency department encounters examined clinician engagement with electronic health record-based…
Doctors reviewed social data more often for opioid use disorder patients, yet this action did not increase medication treatments or fix raci…
Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients
Small pilot study tests sleep environment intervention for ventilated ICU patients
A pilot randomized controlled trial in 17 mechanically ventilated ICU patients with minimal sedation assessed the feasibility of a multi-com…
A small Chilean ICU study shows that dynamic lights, sound masking, and grouped care checks are feasible ways to help ventilated patients sl…
Supraglottic airway versus endotracheal intubation shows no overall survival benefit in out-of-hospital cardiac arrest
Study finds airway device choice doesn't change survival after cardiac arrest outside hospitals
A systematic review and meta-analysis of 14,797 patients with out-of-hospital cardiac arrest found no significant difference in return of sp…
Paramedics saving people whose hearts stop outside hospitals find no survival benefit from complex breathing tubes versus simpler airway dev…
Meta-analysis finds diaphragmatic atrophy and weakness in critically ill patients on ventilation or with sepsis
Why do critically ill patients struggle to breathe on their own? Their diaphragm muscles shrink and weaken
A systematic review and meta-analysis of 187 critically ill patients requiring mechanical ventilation or with sepsis found diaphragmatic fib…
Critically ill patients on ventilators have diaphragm muscles that are 30% smaller and dramatically weaker than normal, explaining their str…
Liposomal bupivacaine, nerve blocks compared to lidocaine for skin graft donor site pain in burn patients
What's the best way to ease pain after skin graft surgery for burn patients?
A two-phase study (RCT and prospective cohort) in 74 burn patients with <20% TBSA burns compared liposomal bupivacaine injection and preoper…
Burn patients with minor injuries face intense donor site pain after skin graft surgery, but doctors haven't yet reported which numbing meth…
PDCA Cycle Intervention Improves Critical Value Management Rate in Primary Healthcare Institutions
Study finds quality improvement program boosts critical lab result handling in clinics
A prospective multicenter cohort study using interrupted time series analysis in 62 primary healthcare institutions in Jiangsu Province foun…
A structured quality program boosted critical lab result handling rates from 93.8% to 98.9% across 62 clinics in Jiangsu Province, China.
Network meta-analysis finds PMX and HA 330 blood purification may reduce mortality in severe septic shock
Two blood purification devices linked to lower death rates in severe septic shock
A Bayesian network meta-analysis of 31 RCTs involving 2678 patients with severe septic shock found that the TORAYMYXIN™ filter (PMX) and HA …
Two specific blood purification devices are linked to lower death rates for patients with severe septic shock compared to standard treatment…
Testosterone gel fails to normalize serum levels in critically ill ICU patients in pilot RCT
Can testosterone gel help critically ill men? A small study finds no clear benefit
A pilot RCT of 30 critically ill ICU patients on vasopressors and mechanical ventilation found 14-day testosterone gel administration did no…
Testosterone gel did not improve hormone levels or safety in critically ill men needing breathing machines and blood pressure support.
Higher baseline chondroitin sulfate predicts greater mortality benefit from restrictive fluid strategy in sepsis
Blood marker may help predict which sepsis patients benefit from less fluid
A biomarker analysis within an RCT of 574 patients with sepsis-associated hypotension found that higher baseline plasma chondroitin sulfate …
A blood marker may help doctors decide which sepsis patients benefit most from receiving less intravenous fluid during treatment.
Balanced salt solution in pediatric septic shock linked to lower AKI and RRT rates versus normal saline
Balanced fluids may reduce kidney injury in children with septic shock, study finds
A meta-analysis of 5 RCTs involving 992 children with septic shock found balanced salt solution (BSS) was not associated with reduced mortal…
Using balanced salt solutions instead of normal saline helps children with septic shock avoid kidney injury and dialysis, a new analysis of …
Remimazolam infusion associated with easier mask ventilation than propofol during anaesthesia induction
Small study finds remimazolam may ease mask ventilation during anesthesia induction
In a randomised trial of 76 adults undergoing elective surgery, continuous remimazolam infusion was associated with less mask ventilation di…
Patients given remimazolam had easier breathing through a mask and more stable blood pressure during surgery induction compared to propofol.
VR and in-person sepsis simulation show similar skill outcomes in medical student pilot study
Can virtual reality teach doctors to spot sepsis as well as real training?
A randomized comparative pilot study of 32 final-year medical students found no statistically significant differences in mQSAT scores or sep…
Virtual reality training helped medical students spot when patients needed intensive care better than traditional practice methods in a new …