Hepatologist-led palliative care matches specialist care for cirrhosis and cancer patients
Trained liver doctors provided care that matched specialists for patients with serious liver disease
A US trial found hepatologist-delivered palliative care noninferior to specialist care for improving quality of life in advanced liver disea…
Patients with advanced liver disease saw similar quality of life improvements when cared for by trained liver doctors versus specialists. Bo…
Endovascular interventions reduce rebleeding risk versus endoscopic cyanoacrylate injection in gastric variceal hemorrhage
Endovascular procedures reduce rebleeding risk for cirrhosis patients compared to injection therapy
This individual patient data meta-analysis compares endovascular interventions with endoscopic cyanoacrylate injection for gastric variceal …
A meta-analysis of 1,240 patients found endovascular procedures significantly lower rebleeding rates than injection therapy, though they car…
Persistent ymrEMVI and ymrTD on post-neoadjuvant MRI predict inferior disease-free and overall survival in rectal cancer patients
Persistent MRI signs linked to worse survival in rectal cancer patients
This systematic review and meta-analysis evaluates prognostic markers in 3932 patients with rectal cancer undergoing neoadjuvant treatment. …
Persistent MRI signs after treatment for rectal cancer are linked to lower survival rates, helping doctors identify patients who may need mo…
Prophylactic clipping after colorectal ESD reduces delayed bleeding risk by 74%
Clipping after colon procedure lowers bleeding risk in adults
This systematic review and meta-analysis of 684 adults found that prophylactic clipping after colorectal endoscopic submucosal dissection si…
A new analysis shows that adding a clip after removing colon polyps significantly lowers the risk of delayed bleeding in adults.
Combining Pentraxin-3 and AFP increases sensitivity to 0.92 for hepatocellular carcinoma diagnosis in chronic liver disease
New blood test helps doctors find liver cancer earlier with better accuracy than old methods alone
This systematic review and meta-analysis evaluated diagnostic markers in adults with chronic liver disease suspected of hepatocellular carci…
A review of 1,179 patients shows a new marker called PTX3 works well for finding liver cancer. Using both PTX3 and AFP together finds more c…
Antimicrobial resistance reaches 33.3% in cirrhosis patients with bacterial infections across global settings
Antimicrobial resistance is rising in cirrhosis patients worldwide
This systematic review and meta-analysis examines bacterial infections in 35,180 adult patients with cirrhosis globally. The analysis report…
A global analysis of 35,180 patients with cirrhosis shows rising antimicrobial resistance and varying mortality risks.
Blood-based ctDNA tests show low sensitivity for advanced colorectal neoplasia in asymptomatic adults
Blood tests miss most early colon cancer signs in average-risk adults
This systematic review and meta-analysis of population-based prospective studies found that blood-based circulating tumour DNA tests have lo…
A large review of blood tests found they often miss early colon cancer signs in average-risk adults, though they work better for advanced di…
1 in 6 dromedary camels in Africa carries Rift Valley Fever antibodies
Seroprevalence of Rift Valley Fever in African camels varies widely by country
A systematic review and meta-analysis of 7444 dromedary camels across 11 African countries found a pooled RVF seroprevalence of 17.25% (95% …
A meta-analysis of 7,444 camels across 11 African nations found infection rates ranging from 32% to 73%, highlighting significant regional d…
General obesity, central obesity, and high triglycerides increase risk of precancerous polyps in colorectal cancer surveillance
Metabolic health matters for colon cancer risk in high-risk surveillance patients
This meta-analysis of 24 observational studies found that metabolic factors such as general obesity, central obesity, hypertension, and high…
Metabolic issues like obesity and diabetes raise the risk of precancerous polyps in people at higher risk for colon cancer. This analysis of…
Higher TyG Index Linked to 4.36-Fold Increased Odds of NAFLD in Large Meta-Analysis
TyG Index Linked to Higher Fatty Liver Risk
This systematic review and meta-analysis of 212,618 participants from observational studies found that higher TyG index levels were associat…
A large analysis found that higher TyG index levels are tied to increased odds of non-alcoholic fatty liver disease. This simple blood test …
Microbiome and metabolite markers may enhance colorectal cancer detection and therapeutic guidance strategies
Microbiome markers may help detect colorectal cancer early
This narrative review discusses microbiome- and metabolite-based markers for colorectal cancer. The authors suggest these markers could impr…
New markers from gut bacteria and metabolites could improve how doctors find colorectal cancer sooner and guide treatment plans.
GLP-1 receptor agonists show potential benefits for metabolic dysfunction-associated steatotic liver disease with acceptable safety
Review shows GLP-1 drugs may help fatty liver disease
This umbrella review evaluated twenty-three meta-analyses and systematic reviews regarding GLP-1 receptor agonists in patients with metaboli…
A review of many studies suggests GLP-1 receptor agonists may improve fatty liver disease, but the evidence is still early and needs stronge…