FDA Approves Kaletra (lopinavir/ritonavir) for HIV-1 Infection in Patients 14 Days and Older
FDA approves Kaletra to treat HIV in adults and children 14 days and older.
The FDA approved Kaletra (lopinavir/ritonavir) for HIV-1 infection in adults and pediatric patients 14 days and older, in combination with o…
The FDA approved Kaletra (lopinavir/ritonavir) for HIV-1 infection in adults and children as young as 14 days. It is used with other HIV med…
FDA Approves Dyna-hex 2 (chlorhexidine gluconate) for Surgical Hand Scrub and Healthcare Personnel Handwash
FDA approves Dyna-hex 2 antiseptic for surgical hand scrubs and healthcare handwash.
The FDA approved Dyna-hex 2 (chlorhexidine gluconate) for use as a surgical hand scrub and healthcare personnel handwash. It significantly r…
The FDA approved Dyna-hex 2 (chlorhexidine gluconate) as a surgical hand scrub and healthcare handwash to reduce bacteria on hands and forea…
Bacteriophages show promise as targeted anti-caries agents in systematic review
Bacteriophages Show Promise Against Cavities
This systematic review summarizes advances in phage-based interventions for dental caries, including phages targeting S. mutans and Actinomy…
Viruses that target bacteria could one day help prevent and treat cavities by killing cavity-causing germs.
Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
New trial to test azithromycin vs doxycycline for pneumonia
This is a protocol for a planned randomized clinical trial involving 1120 adult patients hospitalized with community-acquired pneumonia. No …
A large trial will compare two antibiotic combos for hospitalized pneumonia patients. Which works better?
Digital PCR provides a strong correlation with plaque assays for disinfectant efficacy testing
Digital PCR Shows Strong Correlation with Traditional Disinfectant Testing
This guideline-based validation study evaluates digital PCR (dPCR) as a complement to MS2 plaque assays for assessing virucidal activity. Th…
A new laboratory test shows that digital PCR can accurately track how well disinfectants kill viruses compared to traditional methods.
PPI deprescription associated with 3.66 odds of CDI in hospitalized older adults
Stopping certain acid medications might increase risk of stomach infection
This quasi-interventional substudy of a cluster randomized trial involved 4990 hospitalized older adults taking five or more medications. Th…
A study of nearly 5,000 hospitalized seniors found that stopping specific acid-reducing drugs could actually lead to more frequent infection…
Antimicrobial resistance drivers in human and agricultural sectors contribute to 4.95 million annual deaths
Antimicrobial resistance linked to 4.95 million deaths in 2019
This narrative review examines the global burden of antimicrobial resistance (AMR) across human, livestock, and environmental settings. It i…
A global review finds antimicrobial resistance tied to nearly 5 million deaths in 2019, with overuse of antibiotics a key driver.
Intravesical aminoglycoside instillations reduce recurrent urinary tract infection risk with an IRR of 0.23
New findings show ways to reduce recurring urinary tract infections
This systematic review and meta-analysis of 25 studies evaluates intravesical instillations for preventing recurrent urinary tract infection…
Doctors are looking at new ways to stop repeat urinary tract infections using local treatments like aminoglycosides or hyaluronic acid.
4CMenB vaccine did not reduce infection rates compared to placebo in MSM population
Trial shows 4CMenB vaccine does not prevent gonorrhea or syphilis
This randomized controlled trial evaluated 4CMenB in 587 men who have sex with men (MSM) recently diagnosed with gonorrhea or infectious syp…
A large trial found that a new vaccine did not reduce the rates of gonorrhea or syphilis infections in men at high risk for these conditions…
Comparing antimicrobial resistance to COVID-19 does not reduce antibiotic seeking intentions in US adults
Comparing Antibiotic Resistance to COVID-19 May Not Change Patient Behavior
This randomized online survey of 972 US adults evaluated three messaging types regarding antimicrobial resistance (AMR) and the COVID-19 pan…
Comparing the threat of antibiotic resistance to the COVID-19 pandemic did not change how many people intended to seek unnecessary antibioti…
Ensitrelvir plus standard of care does not improve clinical recovery in hospitalized COVID-19 patients
Trial shows ensitrelvir does not improve recovery for COVID-19
This Phase 3 randomized controlled trial of 589 adults hospitalized with COVID-19 found that ensitrelvir added to standard of care did not s…
A large trial found that adding ensitrelvir to standard care did not speed up clinical recovery for adults hospitalized with COVID-19.
Voriconazole and surgical management successfully treated Aspergillus flavus infection in a patient with spondylolisthesis
Combined surgery and antifungal drugs clear deep spinal infection
This case report and literature review describes the successful treatment of an Aspergillus flavus infection using staged voriconazole and s…
A 74-year-old man with a severe spine infection found relief through a combination of specialized surgery and targeted antifungal medication…