Ceftolozane-tazobactam shows comparable efficacy to ceftazidime-avibactam but lower risk of recurrent infection
New analysis shows lower risk of repeat infections for patients
This systematic review and meta-analysis of 3,361 patients with drug-resistant Pseudomonas aeruginosa infections found no significant differ…
A new review of 3,361 patients found that one specific antibiotic may help prevent recurring infections in those with drug-resistant bacteri…
Mycophenolate mofetil combined with conventional therapy offers best balance of efficacy and safety
Different medications show different benefits for children with kidney inflammation
This network meta-analysis evaluates immunosuppressive regimens for Chinese children with Henoch-Schönlein purpura nephritis. The analysis i…
New data helps doctors choose the best medication combinations to treat kidney inflammation in children with IgA vasculitis.
Treponema phagedenis may contribute to chronic inflammation and lesion recurrence in bovine digital dermatitis
Bacteria may cause lasting infections in cattle with foot rot
This narrative review examines the role of Treponema phagedenis in the pathogenesis and epidemiology of bovine digital dermatitis. The autho…
A specific bacterium might be causing long-term inflammation and recurring sores in cattle, making it harder for them to heal from hoof infe…
Intraosseous vancomycin reduces primary TKA infection risk and improves local tissue concentrations
Injecting antibiotics into bone may lower joint infection risk
This meta-analysis of 13 studies involving 6876 cases found that intraosseous (IO) vancomycin significantly increased bone and fat tissue co…
Delivering vancomycin directly into the bone during hip or knee surgery can significantly lower infection rates and wound complications.
PrEP users show suboptimal vaccination coverage, lowest for HPV at 43%
Vaccination Coverage Remains Low Among People Taking HIV PrEP
This meta-analysis of 13,087 individuals receiving HIV PrEP in routine care found suboptimal vaccination coverage across key vaccines. HBV c…
New data shows that many people taking HIV prevention medication are missing out on other important vaccinations like HPV and Hepatitis B.
Narratives do not increase perceived susceptibility to antibiotic resistance compared to non-narrative information
Narratives Do Not Increase Awareness of Antibiotic Resistance Risks
This randomized controlled trial of 237 Dutch medical students found that narrative formats, whether read or written, did not increase perce…
New research shows that using stories or narratives does not improve how medical students perceive the risks of antibiotic resistance.
C-reactive protein testing impacts antibiotic prescribing rates in acute COPD exacerbations
Blood tests may help doctors decide when to use antibiotics
Integrating C-reactive protein tests into primary care may significantly reduce unnecessary antibiotic prescriptions for patients with acute…
A new look at blood tests suggests a specific test can help doctors decide if patients with lung disease truly need antibiotics.
FDA Approves Veklury (remdesivir) for COVID-19 in Adults and Pediatric Patients
FDA approves Veklury to treat COVID-19 in adults and children.
The FDA approved Veklury (remdesivir) for the treatment of COVID-19 in adults and pediatric patients (birth to less than 18 years weighing a…
The FDA approved Veklury (remdesivir) for treating COVID-19 in adults and children who are hospitalized or at high risk of severe disease. T…
Skin colonization by Candida auris is a key factor in high transmissibility and outbreak potential
Skin Colonization Key to Candida auris Spread
This systematic review examines the epidemiological characteristics, microbiota alterations, and decolonization strategies for Candida auris…
Candida auris spreads easily because it colonizes skin. New review explains why and what to do.
Hydrogen sulfide mediates bacterial antibiotic tolerance through iron chelation, efflux pump activation, and metabolic dormancy
Hydrogen Sulfide May Help Overcome Bacterial Antibiotic Tolerance
This systematic review synthesizes the role of hydrogen sulfide (H2S) in mediating multidrug tolerance in bacteria. The authors identify thr…
New research identifies how hydrogen sulfide helps bacteria resist antibiotics, offering a potential new way to target and eliminate persist…
FDA Approves Dyna-hex 4 (chlorhexidine gluconate) for Healthcare Personnel Handwash
FDA approves Dyna-hex 4 for handwashing and skin cleansing.
The FDA approved Dyna-hex 4 (chlorhexidine gluconate) for healthcare personnel handwash, skin wound cleansing, and general skin cleansing. T…
The FDA approved Dyna-hex 4 (chlorhexidine gluconate) for use as a handwash and skin cleanser in healthcare settings. It helps reduce bacter…
FDA Approves Kaletra (lopinavir/ritonavir) for HIV-1 Infection in Adults and Children
FDA approves new HIV drug Kaletra for adults and children.
FDA approved Kaletra (lopinavir/ritonavir) for treatment of HIV-1 infection in adults and pediatric patients 14 days and older, in combinati…
The FDA approved Kaletra (lopinavir/ritonavir) to treat HIV-1 infection in adults and children aged 14 days and older. It is used with other…