Triple antibiotic paste shows stronger antimicrobial performance than calcium hydroxide for persistent endodontic infections
Triple antibiotic paste beats calcium hydroxide for killing stubborn tooth infections
This systematic review with exploratory meta-analysis synthesized twelve studies on intracanal medicaments for persistent endodontic infecti…
Triple antibiotic paste showed stronger power to kill bacteria than calcium hydroxide, but results varied widely across different studies.
Microbial arsenic transformations influence methane oxidation, denitrification, and carbon fixation in high-arsenic environments
Microbes in arsenic-rich soil may change how much greenhouse gas the planet releases
This narrative review examines microbial transformations of arsenic in naturally high-arsenic environments. The authors synthesize evidence …
Microbes in arsenic-rich environments might alter greenhouse gas emissions. This review explains how these tiny organisms link arsenic chang…
One in six blood donors in Cameroon carries Plasmodium infection, meta-analysis finds
1 in 6 blood donors in Cameroon carries malaria parasite
A systematic review and meta-analysis of 18 studies (~12,500 donations) found a 16.6% pooled prevalence of Plasmodium spp. in Cameroonian bl…
A review of 18 studies finds 16.6% of blood donations in Cameroon contain Plasmodium, the malaria parasite.
Pooled cytomegalovirus retinitis prevalence is 3% among people with HIV in sub-Saharan Africa
Cytomegalovirus retinitis risk varies across sub-Saharan Africa regions
This systematic review and meta-analysis synthesized data from 1931 people living with HIV in sub-Saharan Africa. The pooled prevalence of c…
A meta-analysis found that cytomegalovirus retinitis prevalence in people living with HIV ranges from less than 1% to 7% depending on the re…
Biofeedback therapy improves constipation response rates and symptom scores in adults compared to control groups
Biofeedback therapy helps more adults with chronic constipation than usual care
A meta-analysis of 19 trials shows biofeedback therapy significantly boosts response rates and bowel frequency for chronic constipation. Whi…
Biofeedback therapy significantly improved bowel movement frequency and quality of life for adults with chronic constipation, though study l…
Narrative review examines microorganisms in breast cancer with limited evidence from cross-sectional studies and models
Review of microorganisms and breast cancer evidence remains uncertain
This narrative review addresses the role of microorganisms in breast cancer. The authors note that the majority of evidence originates from …
A review of microorganisms and breast cancer shows evidence is weak because most data comes from cross-sectional studies and lab models.
Review of animal models for allergic fungal airway disease and asthma
Animal models reveal how fungi trigger severe asthma
This narrative review examines animal models for allergic fungal airway disease, allergic bronchopulmonary aspergillosis, and asthma. The au…
New review shows spore-based animal models better mimic human allergic fungal airway disease, pointing to new treatment targets.
MESNA-assisted surgery disrupts disease-associated microbiota equilibrium in paediatric cholesteatomatous chronic otitis media
Early data suggest MESNA may help restore ear bacteria in children with chronic ear infections
This observational review characterizes the microbiota of paediatric patients with cholesteatomatous chronic otitis media (CCOM) and evaluat…
A small review links MESNA-assisted surgery to changes in ear bacteria, offering hope for preventing infection return in children.
FDA Approves Hepcludex (bulevirtide) for Chronic Hepatitis Delta Virus Infection
FDA approves new drug Hepcludex for chronic hepatitis delta infection.
FDA approved Hepcludex (bulevirtide) for chronic HDV infection in adults without cirrhosis or with compensated cirrhosis. Approval was based…
The FDA approved Hepcludex (bulevirtide) for adults with chronic hepatitis delta virus (HDV) infection who have no or compensated cirrhosis.…
Review discusses sequential eradication strategies using EGCG, baicalin, and other compounds for potential therapeutic applications
Sequential herbal strategy faces manufacturing hurdles before clinical use
This review synthesizes evidence regarding a sequential eradication strategy involving barrier disruption, metabolic resuscitation, and term…
A review suggests a multi-step herbal approach for disease control, but experts warn that turning these complex mixtures into safe, approved…
Review of influenza A and secondary bacterial infections identifies critical knowledge gaps
Review highlights gaps in flu and secondary infection care
This is a narrative review on influenza A virus infection, secondary bacterial infection, and nosocomial infection. The authors synthesize c…
A new review points out major missing knowledge about flu and related infections. It calls for more research to help patients.
Meta-analysis finds high fluoroquinolone resistance in E. coli causing UTIs globally
1 in 3 UTI E. coli cases now resist common antibiotics
This meta-analysis of 36 studies reports a pooled fluoroquinolone resistance prevalence of 31.09% in E. coli from UTIs. Resistance varied by…
A global review finds that nearly a third of E. coli from UTIs are resistant to key fluoroquinolone antibiotics, making infections harder to…