Tablet-guided training improves HIV index case testing fidelity by 30.5 percentage points
Tablet training boosts HIV counseling skills in Malawi
This cluster randomized controlled trial of 306 lay health care workers in Malawi found that tablet-guided training improved knowledge, atti…
Adding tablet-guided training to standard HIV counseling education improved knowledge and skills among health workers in Malawi.
Fidaxomicin and vancomycin pulse and taper regimens show potential for reducing Clostridioides difficile recurrence
Fidaxomicin and Vancomycin Pulse Regimens May Reduce Infection Recurrence
Researchers evaluated various treatment regimens, including fidaxomicin and vancomycin pulse and taper strategies, for managing Clostridioid…
New analysis suggests that specific dosing schedules for fidaxomicin and vancomycin may be more effective at preventing recurring C. diffici…
Targeted interventions increase condom use and HIV knowledge among long-distance truck drivers
Targeted programs improve HIV prevention for long distance truck drivers
This systematic review and meta-analysis of 24 studies evaluated targeted interventions for HIV prevention in long-distance truck drivers. R…
Specific outreach programs help long distance truck drivers increase condom use and knowledge to better prevent HIV infection.
Dual-ART and triple-ART both reduce plasma biomarkers of immune activation and neuronal injury
Dual-ART Therapy Shows Lower Brain Inflammation for People with HIV
This randomized controlled trial of 238 adults initiating ART found that both dual-ART and triple-ART regimens significantly reduced markers…
A new trial shows that a specific dual-drug treatment may lower markers of brain inflammation and injury in adults living with HIV.
Sotorasib resistance linked to transformation to pulmonary giant cell carcinoma in KRAS G12C lung adenocarcinoma
Lung cancer can change form after targeted drug treatment
A case report with literature review describes a 71-year-old man with KRAS G12C-mutant lung adenocarcinoma whose tumor transformed to pulmon…
A man's lung cancer transformed into a more aggressive type after taking the targeted drug sotorasib, highlighting the need for re-biopsy wh…
Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements
Magnesium Phosphate Cements Show Better Biological Interaction Than Calcium Options
This mini review examines the properties of magnesium phosphate cements (MPCs) compared to calcium phosphate cements (CPCs). The authors con…
New research suggests magnesium phosphate cements may offer better biological interactions and faster resorption than traditional calcium ph…
Chlorhexidine reduces alveolar osteitis risk by 42.9% after third molar surgery
Chlorhexidine Reduces Risk of Painful Infection After Wisdom Tooth Surgery
This meta-analysis found that chlorhexidine supplementation after third molar surgery significantly reduces the incidence of alveolar osteit…
A review of clinical data shows that using chlorhexidine after wisdom tooth surgery can significantly lower the risk of painful infections.
NLRP3 inhibition and IL-1 receptor blockade attenuate musculoskeletal pathology in alphavirus infections
Targeting specific proteins may reduce joint damage from viral infections
This mini review synthesizes preclinical data regarding NLRP3 inflammasome activation during Chikungunya, Ross River, and Mayaro virus infec…
New research suggests that blocking certain inflammatory pathways could protect bones and joints from damage caused by Chikungunya, Mayaro, …
Antimicrobial additives in resin-based endodontic sealers enhance antibacterial activity against Enterococcus faecalis
Additives help fight bacteria in root canal infection treatments
This scoping review of 33 studies synthesized the impact of antimicrobial additives like nanoparticles and chlorhexidine on resin-based endo…
Adding antimicrobial agents to dental sealers can better fight deep infections while keeping the material safe and stable.
Multimodal laboratory diagnostics improve detection of biofilm-encased pathogens and polymicrobial infections in bone and joint infections
New Laboratory Tools Improve Diagnosis of Bone and Joint Infections
This narrative review synthesizes current evidence regarding laboratory diagnostics for bone and joint infections, including serum markers, …
Advanced molecular tests and tissue processing are improving how doctors identify complex bone and joint infections that traditional culture…
Image-guided RFA and MWA show comparable efficacy and safety for small to medium hepatocellular carcinoma
Radiofrequency and microwave ablation show similar results for liver cancer
This meta-analysis of 19 studies compared image-guided radiofrequency ablation (RFA) and microwave ablation (MWA) for small to medium hepato…
Two common types of heat-based treatments for small to medium liver cancer show nearly identical success rates and safety profiles.
Syphilis prevalence is 5.20-fold higher in low-income countries among forcibly displaced populations
High Rates of Syphilis Found Among Displaced Populations
This meta-analysis of 1.1 million test results across 82 reports evaluates the prevalence of syphilis, gonorrhea, chlamydia, and trichomonia…
A large-scale review reveals high rates of syphilis and other infections among refugees, highlighting the need for better screening in these…