Gay men show higher rates of PrEP awareness and use than bisexual men
Gay men more likely to use HIV prevention tools
This meta-analysis of 514,543 individuals identified significantly higher rates of PrEP awareness and usage among gay men compared to bisexu…
New data shows significant gaps in PrEP awareness and use among bisexual men compared to gay men, highlighting a need for targeted outreach.
Conjugation governs the spread of resistance genes in bacterial populations across ecological compartments
Gene swapping drives the spread of antibiotic resistance in bacteria
This narrative review examines bacterial populations and the spread of resistance genes. The authors argue that conjugation governs the spre…
A review shows that bacteria sharing genes spreads resistance faster than simple mutation. This process happens across different environment…
Early-life microbiome shapes allergic, metabolic, and respiratory disease risk
Gut and Lung Microbiome in Early Life Linked to Health
This narrative review synthesizes evidence on how the human gut and lung microbiome in early life influences allergic diseases, metabolic di…
A review suggests the gut and lung microbiome in early life may influence allergies, metabolism, and respiratory health.
Water buffalo act as reservoirs for infectious diseases in mixed livestock systems
Water Buffalo May Spread Diseases to Other Livestock
This systematic review analyzes 180 articles regarding infectious diseases in water buffalo. The authors conclude that these animals are inc…
A review of 180 articles suggests water buffalo act as disease reservoirs, meaning they can pass infections to other animals in mixed farmin…
PEG-IFN plus novel agents may boost functional cure in chronic hepatitis B
Combination therapies may improve functional cure rates for chronic hepatitis B
This narrative review examines combining pegylated interferon-α with novel immunotherapies (antigen-reduction strategies, therapeutic vaccin…
A review suggests combining pegylated interferon with new immunotherapies could help achieve functional cure in chronic hepatitis B patients…
Antibiotic prophylaxis reduces UTI risk in children with VUR but increases antibiotic resistance
Taking daily antibiotics lowers UTI risk but raises resistance chances for young patients with reflux
This systematic review and meta-analysis of 2577 children with vesicoureteral reflux found that continuous antibiotic prophylaxis reduced UT…
A large review found that daily antibiotics reduce urinary infections in kids with reflux. However, this treatment also makes bacteria harde…
CDK4/6 inhibitors show therapeutic potential in advanced gastrointestinal cancers, review finds
CDK4/6 inhibitors show promise against digestive cancers
This narrative review examines the role of CDK4/6 inhibitors (palbociclib, ribociclib, abemaciclib) in advanced gastrointestinal cancers. It…
New review reveals how CDK4/6 drugs might work against stomach, colon, and liver cancers, but hurdles remain.
Microbial metabolites may promote or suppress cancer progression through inflammation, DNA damage, or immune modulation
Microbial metabolites may drive cancer growth or stop it through inflammation and DNA damage
This narrative review examines the role of microbial metabolites in carcinogenesis and cancer progression across multiple malignancies. The …
Microbial metabolites can promote cancer growth via inflammation or suppress it through immune changes, but we need more proof before using …
Apodemus mice are key reservoirs for Borrelia and Neoehrlichia, but landscape drives tick-borne pathogen risk
Mice Spread Tick-Borne Diseases in Europe, Review Finds
This narrative review examines the role of European Apodemus spp. as reservoirs for tick-borne pathogens. Apodemus mice are confirmed reserv…
Mice and voles are key spreaders of tick-borne diseases in Europe, but their role depends on the environment.
HIV linked to lower odds of post-TB lung disease; undernutrition raises risk
Undernutrition and HIV may lower or raise lung damage risk after tuberculosis in low-income nations
This systematic review and meta-analysis of 41 studies in LMICs found that HIV was associated with reduced odds of spirometry-defined post-t…
New analysis of data from low-income countries shows mixed results on how HIV, diabetes, and poor nutrition affect lung health after tubercu…
Standardized environmental AMR detection needed for regulatory interpretation and concern tiering
Standardizing environmental antibiotic data helps regulators assess antibiotic resistance risks
This review argues that environmental detection of antibiotics and antimicrobial resistance genes/bacteria becomes more useful when evidence…
A review explains how combining antibiotic exposure data with resistance evidence improves how regulators evaluate environmental antibiotic …
Inhaled antibiotics improve clinical cure and reduce mortality in ventilator-associated pneumonia
Inhaled antibiotics help cure pneumonia and lower death risk in ICU patients
This systematic review and meta-analysis of adjunctive inhaled antibiotics for ventilator-associated pneumonia found significantly improved …
Adding inhaled antibiotics to standard care improved cure rates and reduced death in patients with ventilator-associated pneumonia.