Review of topical phage therapy for wounds and burns notes dosing standardization gaps
Why Topical Phage Therapy Needs a New Plan
This review examines the use of topical phage therapy for wound and burn conditions. The authors synthesize that effective treatment of matu…
Topical phage therapy works best when doctors standardize doses and delivery methods to break through bacterial shields in tough wounds and …
Integrative review finds fitness consequences of ESBL and AmpC resistance plasmids in E. coli are assay-dependent
Why Resistance Spreads So Fast
This integrative review synthesizes 40 studies on fitness consequences of plasmid-mediated ESBL and AmpC resistance in E. coli across human,…
Tiny DNA USB drives let gut bacteria swap antibiotic resistance genes, causing infections to spread faster than ever before.
Narrative review explores vaginal microbiota transplantation for dysbiosis and sexual quality of life
Review explores vaginal microbiota transplantation for treating dysbiosis and improving sexual quality of life in women.
This narrative review examines vaginal microbiota transplantation (VMT) for women with genital tract dysbiosis and diminished sexual quality…
This narrative review examines vaginal microbiota transplantation (VMT) as a potential treatment for vaginal dysbiosis and diminished sexual…
Narrative review summarizes drug classes for coronavirus infection, including small molecules and Traditional Chinese Medicine.
What small and large drugs might do for coronavirus infections remains unclear in this review.
This narrative review surveys drug classes like small-molecule drugs, macromolecular drugs, peptides, polymers, and Traditional Chinese Medi…
Coronavirus treatments range from small-molecule drugs to Traditional Chinese Medicine, but this review finds the evidence remains incomplet…
Narrative review examines carbapenem-resistant E. coli and One Health approach in AMR governance
Review offers theoretical support for managing carbapenem-resistant E. coli in public health
This narrative review explores carbapenem-resistant Escherichia coli and its implications for antimicrobial resistance governance. It offers…
This narrative review examined carbapenem-resistant Escherichia coli, a type of bacteria that resists strong antibiotics. The article discus…
Narrative review suggests combination regimens over vancomycin monotherapy for Elizabethkingia meningoseptica infections
Is vancomycin alone safe for a rare infection that might actually need a stronger team approach?
This narrative review addresses Elizabethkingia meningoseptica infections, noting that frequent misidentification between E. meningoseptica …
Doctors should combine vancomycin with other antibiotics instead of using it alone to treat rare Elizabethkingia infections, because relying…
Ugandan malaria patients with PfKelch13 mutant parasites showed no increased gametocyte production or mosquito transmission.
Uganda Malaria Study: Does Resistance Stop Spreading?
This cohort study evaluated 235 Ugandan malaria patients at Kalongo Hospital for PfKelch13 mutations (C469Y or A675V) compared to wild-type …
Resistant malaria parasites in Uganda do not spread more easily to mosquitoes, offering hope that current treatments remain effective agains…
Retrospective cohort study assesses Acinetobacter baumannii prevalence and resistance in ventilator-associated infections.
ICU Infection Risk Skyrockets Without Local Drug Data
This retrospective observational cohort analyzed 3,540 non-duplicate clinical isolates from a tertiary-care ICU in South India. The study ev…
ICU patients with breathing tubes face higher infection risks when doctors lack fresh local data on which antibiotics actually work against …
Retrospective cohort study links prior antibiotic exposure and Gram-negative infections to high MDR rates in adult patients with chronic liver disease.
High antibiotic resistance found in infections among chronic liver disease patients in India
This retrospective observational cohort study evaluated 317 adult patients with chronic liver disease and culture-positive bacterial infecti…
In India, nearly 80% of E. coli and K. pneumoniae infections in chronic liver disease patients are resistant to multiple antibiotics.
PBMC gene expression profiles differentiate refractory Mycoplasma pneumoniae pneumonia in children
New Blood Test Distinguishes Severe Lung Infection Early
This cohort study of 349 children identified peripheral blood mononuclear cell gene expression profiles as potential biomarkers for refracto…
A new four-gene blood test helps doctors spot severe, hard-to-treat pneumonia in children before symptoms get too bad to fix easily.
Meta-analysis compares post-acute risks after SARS-CoV-2 versus other respiratory viral infections
Do You Have Post-Viral Symptoms?
This systematic review and meta-analysis of 22 studies synthesizes evidence on persistent symptoms after SARS-CoV-2 infection compared to ot…
Many post-viral symptoms like fatigue and brain fog happen after any bad virus, not just COVID, though trouble breathing and heart palpitati…
Review of food insecurity and delayed TB treatment initiation in Botswana
Hungry Minds: Why Poverty Delays TB Care
This observational review examined food insecurity and delayed TB treatment initiation among 180 people newly diagnosed with TB in Gaborone,…
Fixing hunger alone might not be enough; we must also treat the sadness and worry that keep patients from seeking help.