Evaluating Enhanced Intervention Strategies for Trachoma Elimination in Rural Ethiopian Communities
Enhanced treatment shows no extra benefit for children with trachoma
A cluster-randomized trial evaluates if adding fly control and hygiene behaviors to azithromycin dosing reduces trachoma prevalence.
A three-year study in Ethiopia found that adding extra fly control and hygiene measures did not lower infection rates more than standard dru…
Favipiravir co-administration with lopinavir-ritonavir increased favipiravir clearance by twofold in COVID-19 patients
Trial shows favipiravir and lopinavir-ritonavir do not stop COVID-19
This Phase 2a randomized, double-blind, 2x2 factorial placebo-controlled trial evaluated favipiravir and lopinavir-ritonavir in patients wit…
A new trial reveals that combining favipiravir with lopinavir-ritonavir did not show antiviral activity against the virus in patients with C…
Health insurance navigation after HIV testing was acceptable for 50.0% of eligible men
Insurance Navigation Helps Men with HIV Get Better Coverage
This randomized structural intervention involved 230 Black/African American and Hispanic/Latino men who have sex with men in Chicago. Half o…
A new study shows that offering immediate help with health insurance can successfully connect men living with HIV to better coverage and car…
Long-acting injectable antiretroviral therapy shows equivalence to oral therapy in meta-analysis of 9 RCTs
Injectable HIV therapy matches pills in global trials
This meta-analysis of 9 head-to-head RCTs (n=3208) comparing long-acting injectable (LAI) and oral antiretroviral therapies found no signifi…
A new analysis finds long-acting injectable HIV meds work as well as daily pills, but results may vary by region.
Colistin-based inhalation regimens rank highest for clinical response in multidrug-resistant Acinetobacter baumannii pneumonia
Colistin Inhalation Tops for Drug-Resistant Pneumonia
This network meta-analysis of 1420 patients with multidrug-resistant Acinetobacter baumannii (MDRAB) pneumonia compared colistin, tigecyclin…
For tough pneumonia, inhaled colistin works best, but sulbactam is a good alternative without the toxicity.
Cefmetazole or flomoxef linked to higher 14-day mortality vs carbapenems in ESBL-PE bacteremia
Trial Shows Carbapenems May Outperform Other Antibiotics for Bacteremia
This meta-analysis of 975 adults with ESBL-producing Enterobacterales bacteremia found that cefmetazole or flomoxef was associated with sign…
New data suggests carbapenem antibiotics may offer better early survival rates than cefmetazole or flomoxef for patients with specific blood…
APOE ε4 status does not significantly impact neurocognitive performance in adults with HIV infection
APOE Status Does Not Impact Cognitive Health in HIV Patients
This meta-analysis of 2610 adults with HIV found no significant difference in cognitive performance or diagnosis of neurocognitive impairmen…
A large review of data suggests that the APOE e4 gene does not change cognitive performance or impairment for adults living with HIV.
NF-kB pathway serves as a unifying hub for molecular and clinical phenotypes in post-acute infection syndrome
New research identifies shared biological markers for chronic fatigue conditions
This systematic literature review synthesized 142 studies to identify biomarkers and pathomechanisms for post-acute infection syndrome (PAIS…
Researchers identified a common biological pathway linked to post-acute infection syndrome, which may help explain the underlying causes of …
Triple antibiotic paste and calcium hydroxide show comparable success in necrotic immature teeth
Triple Antibiotic Paste Shows Success for Necrotic Immature Teeth
This meta-analysis evaluated the clinical success rates of triple antibiotic paste, double antibiotic paste, and calcium hydroxide for regen…
New research shows triple antibiotic paste and calcium hydroxide are both highly effective at saving immature teeth with infections.
Three-variable stratification tool identifies risk of invasive pulmonary aspergillosis in SFTS patients
New Tool Helps Identify Fungal Infection Risk in SFTS Patients
This meta-analysis and systematic review evaluates a three-variable diagnostic stratification tool for identifying invasive pulmonary asperg…
A new diagnostic tool helps doctors identify patients with severe fever and thrombocytopenia who are at higher risk for a specific fungal in…
0.01% atropine reduces axial length by 0.04 mm/year in children with myopia
Low Dose Atropine Shows Mixed Results for Children with Myopia
This meta-analysis of randomized controlled trials evaluates the efficacy of 0.01% atropine for managing myopia in children. The analysis fo…
A low dose of atropine may slow eye growth in children with myopia, though its effects are less consistent than stronger doses.
Salmonella prevalence in bovine deep tissue lymph nodes reaches 10.8% across 33 studies
Salmonella found in 10.8% of beef lymph nodes
This meta-analysis of 33 studies evaluates Salmonella prevalence and concentration in bovine deep tissue lymph nodes (DTLNs). The analysis f…
A meta-analysis of 33 studies finds Salmonella in about 1 in 10 deep tissue lymph nodes from cattle, with higher rates in warm weather and f…