Antibiotic use and risk factors linked to AAD and CDAD in critically ill patients
Nearly 1 in 3 ICU Patients Get Antibiotic Diarrhea, New Analysis Finds
This systematic review and meta-analysis evaluated the incidence of antibiotic-associated diarrhea (AAD) and Clostridioides difficile-associ…
Nearly 1 in 3 critically ill patients develop antibiotic diarrhea, a common side effect that delays recovery and affects older adults and di…
Systematic review examines innate immune recognition and PRR activation in HPV infection and cervical cancer progression.
How HPV Outsmarts Your Body's First Line of Defense
This mini-review synthesizes evidence regarding innate immune recognition, pattern recognition receptor activation, and HPV evasion strategi…
HPV evades the immune system by silencing its alarms, fueling cervical cancer and pointing to new ways to prevent it.
Review examines type VII secretion system roles in Mycobacterium tuberculosis immune evasion
How tuberculosis bacteria hide from your immune system using special tools
This narrative review synthesizes evidence on Mycobacterium tuberculosis type VII secretion system (ESX-associated genes) functions. It desc…
Tuberculosis bacteria use secret tools to steal iron, hide inside your cells, and slip past immune guards to cause serious illness.
Gut microbiota signatures in preterm infants correlate with neurodevelopmental impairment risk at three months corrected age.
Tiny Gut Clues May Predict Brain Risks in Preemies
This prospective, matched, longitudinal multi-omics study evaluated preterm infants to identify early biomarkers for neurodevelopmental impa…
A simple stool sample from a preterm baby may one day reveal who needs extra brain support long before any symptoms show up.
MDRO detection rates increased during COVID-19 policy phases in Chinese inpatients with hospital-acquired infections.
Superbugs Quietly Shifted During COVID, Hospital Data Reveals
A retrospective cohort study of 2,669 adult inpatients with culture-confirmed hospital-acquired infections at a Chinese tertiary hospital fo…
Hospital data shows superbugs quietly shifted during COVID lockdowns, making older adults and long-stay patients face higher infection risks…
Retrospective study finds low resistance to key antibiotics in TB patients with UTIs
When TB Treatment Hits a Wall: The Hidden Bladder Problem
A retrospective cohort study of 1,151 bacterial strains from tuberculosis patients with urinary tract infections at a single hospital found …
Tuberculosis patients with urinary infections face drug-resistant bacteria, but a five-year hospital review reveals which antibiotics still …
Meta-analysis finds vonoprazan-based therapies achieve 94% H. pylori eradication in Asian populations
The Two-Drug Combo Clearing Stomach Bacteria Where Others Are Failing
A systematic review and meta-analysis of 7,498 Asian patients with Helicobacter pylori infection compared vonoprazan-amoxicillin regimens to…
A new two-drug combo clears stomach bacteria in 94% of Asian patients, outperforming standard treatments where others are failing.
Nevirapine plus lamivudine and zidovudine improved lymphocyte counts and reduced adverse effects versus efavirenz in HIV patients.
New HIV drug combo showed fewer side effects and better immune markers in small trial
This randomized controlled trial enrolled 100 patients with HIV/AIDS in a hospital setting. Participants received either lamivudine plus zid…
A new HIV drug combo boosted immune cells and caused fewer side effects than the standard alternative in a recent trial.
AZD7442 showed no benefit over placebo and increased rehospitalization risk in hospitalized COVID-19 adults.
A COVID Antibody Drug That Looked Promising Didn't Deliver
This Phase 3 randomized multicentre trial evaluated tixagevimab-cilgavimab (AZD7442) versus placebo in 237 hospitalized adults with PCR-conf…
A rigorous 15-month trial found that a promising COVID antibody drug offered no clinical benefit to hospitalized patients and led to more re…
Meta-analysis finds 30.5% breakthrough UTI rate in children with VUR on antibiotic prophylaxis
A Scorecard to Spot Kids at Highest Risk of Kidney Infections
A meta-analysis of 24 cohort studies (n=3,264) in children with vesicoureteral reflux on continuous antibiotic prophylaxis found a pooled br…
A new eight-clue scorecard helps doctors spot which children on daily antibiotics are most likely to still get a kidney infection.
High-volume interval exercise linked to higher enjoyment in people with HIV versus healthy controls
High-intensity interval exercise boosted enjoyment in people living with HIV compared to healthy controls
A single-blind crossover study of 11 people living with HIV and 11 healthy controls found that high-volume high-intensity interval exercise …
People living with HIV reported higher enjoyment during high-volume intense workouts compared to healthy controls in a new study.
Short-course beta-lactam prophylaxis reduces early-onset VAP in mechanically ventilated patients with acute brain injury.
Short Antibiotics Cut Early Lung Infections in Brain Injury Patients
This systematic review and meta-analysis evaluated short-course systemic beta-lactam antibiotic prophylaxis versus control in 1,673 mechanic…
Short antibiotic courses cut early lung infections in brain injury patients on ventilators, reducing hospital stays without increasing death…