Parkinson's institutionalisation risk 37.2% by 10 years; older age, motor severity, cognition predict
Parkinson's Risk Factors Predict Nursing Home Placement
This meta-analysis of European incidence cohorts (n=1046) found a 37.2% cumulative incidence of institutionalisation by 10 years in people w…
Nearly 4 in 10 people with Parkinson's enter a nursing home within 10 years. Older age, worse motor symptoms, and lower cognitive scores rai…
Clinical reasoning frameworks help differentiate ALS from degenerative cervical myelopathy despite clinical overlap
Doctors find ways to tell ALS apart from neck issues
This narrative review examines the diagnostic differentiation between amyotrophic lateral sclerosis and degenerative cervical myelopathy. Th…
Telling the difference between ALS and cervical myelopathy is hard because they share many symptoms, but new tools help doctors get it right…
Autonomic gastrointestinal dysfunction occurs in 31.4% of people with multiple sclerosis
Many people with multiple sclerosis experience significant digestive issues
This meta-analysis of 1,272,170 individuals identifies high prevalence rates for various gastrointestinal symptoms and disorders in patients…
Over 30% of people with multiple sclerosis experience autonomic gut dysfunction, making digestive health a major part of managing the condit…
Stand phase duration and relative paw placement are candidate surrogate markers for dynamic spasticity
CatWalk System Shows Potential for Tracking Spasticity in Rodent Models
This systematic review evaluates the CatWalk system as a tool for assessing spasticity-related gait abnormalities in rodent models. While st…
A new review looks at how the CatWalk system can track walking changes in rodent models to help identify markers of dynamic spasticity.
Prefrontal iTBS reduces methamphetamine craving (SMD -1.03) but shows no effect on nicotine craving
Brain Stimulation May Reduce Craving in Methamphetamine Use Disorder
This systematic review and meta-analysis of 9 trials involving 556 participants found that prefrontal iTBS significantly reduced cravings in…
A review of clinical trials suggests that a specific type of brain stimulation may lower cravings for methamphetamine.
Acupuncture-related therapy may aid sudden hearing loss via central mechanisms
Acupuncture may help sudden hearing loss, review suggests
This narrative review synthesizes preliminary evidence that acupuncture-related therapy may promote hearing recovery and alleviate symptoms …
A review suggests acupuncture may aid sudden hearing loss recovery, but rigorous studies are needed to confirm.
Microvascular alteration is a statistically significant determinant for diabetic peripheral neuropathy prevalence
New data reveals key drivers of nerve damage in diabetes
This meta-analysis of 83,560 patients across 24 countries identified a global diabetic peripheral neuropathy (DPN) prevalence of 57.42% (95%…
Over half of people with diabetes suffer from nerve damage, but new data highlights specific blood vessel changes as a primary driver of the…
Endovascular thrombectomy is effective for specific large-vessel occlusion and late-window ischemic stroke scenarios
Endovascular Thrombectomy Shows Promise for Specific Stroke Scenarios
This mini-review synthesizes evidence regarding endovascular thrombectomy (EVT) for acute ischemic stroke caused by large-vessel occlusion. …
New evidence highlights how targeted endovascular thrombectomy can help specific types of large-vessel stroke while requiring careful patien…
tDCS Boosts Consciousness Recovery in Brain Injury Meta-Analysis
Brain stimulation shows promise for patients with disorders of consciousness
Meta-analysis of 330 patients shows active tDCS improves CRS-R scores vs sham, suggesting a potential role in disorders of consciousness.
A review of clinical trials suggests that a specific type of brain stimulation may help people with disorders of consciousness show more awa…
Thirty-two factors including low BMI, advanced age, and frailty are associated with stroke-related sarcopenia
Factors Linked to Muscle Loss After Stroke Identified
This scoping review of 32 studies identifies 32 diverse factors associated with stroke-related sarcopenia. These include physical metrics li…
New research identifies over 30 different factors, including age and nutrition, that are linked to muscle loss in people who have suffered a…
Corticosteroids remain first-line for peripheral facial palsy while antiviral agents show limited utility
New Options for Managing Facial Palsy and Hemifacial Spasms
This narrative review synthesizes management strategies for peripheral facial palsy, including corticosteroids, antivirals, and neuromodulat…
New treatments like pulsed radiofrequency show promise for hemifacial spasms, while antiviral drugs may only help in severe cases of facial …
Five anchor clinical phenotypes provide a framework for individualized management of persistent postural-perceptual dizziness
New framework helps doctors treat persistent postural-perceptual dizziness
This narrative review synthesizes a proposed framework to manage persistent postural-perceptual dizziness (PPPD) by categorizing patients in…
A new clinical framework identifies five distinct types of chronic dizziness to help doctors create personalized treatment plans for patient…