Framingham cohort links longitudinal brain atrophy patterns to cognitive decline and AD biomarkers in community-based participants
Brain shrinkage patterns predict Alzheimer's risk in older adults
This community-based cohort study of 300 participants from the Framingham Heart Study analyzed longitudinal brain atrophy patterns using MRI…
A study of 300 older adults found specific brain shrinkage patterns that strongly predict Alzheimer's disease and worse thinking skills.
Meta-analysis shows repetitive peripheral magnetic stimulation effects on stroke motor recovery
New rules for magnetic therapy boost arm recovery after stroke
This meta-analysis of 14 trials involving 580 stroke patients evaluates the effects of repetitive peripheral magnetic stimulation (rPMS) on …
New magnetic therapy rules help stroke patients regain arm strength faster when used for the right length of time
Five-variable admission model predicts 90-day outcomes in 245 aneurysmal subarachnoid hemorrhage patients
New model predicts recovery after aneurysmal subarachnoid hemorrhage
This single-center cohort study evaluated an admission-based five-variable model in 245 consecutive treatment-eligible patients with aneurys…
A simple 5-factor model at hospital admission accurately predicts 90-day recovery after bleeding stroke.
SBP trajectory clusters associated with acute kidney injury risk in spontaneous intracerebral hemorrhage patients
Blood Pressure Patterns Linked to Kidney Injury in Brain Bleed Patients
This retrospective cohort study examined 233 adults in the intensive care unit with spontaneous intracerebral hemorrhage.
In ICU patients with brain bleeds, specific blood pressure changes were linked to higher odds of kidney injury, while other outcomes showed …
Clinical features and treatment responses in 40 male patients with VEXAS syndrome
HMA treatment shows promise for VEXAS syndrome patients
This retrospective multicenter study of 40 male patients with VEXAS syndrome evaluated clinical features and various treatment responses.
New data on VEXAS syndrome suggests that hypomethylating agents may help improve clinical and biological responses in men.
A prediction model for futile reperfusion after endovascular thrombectomy in large vessel occlusion stroke
New Model Predicts Futile Stroke Reperfusion After Clot Removal
This retrospective cohort study developed a model using clinical, imaging, and laboratory markers to predict futile reperfusion after endova…
A new tool combining clinical, imaging, and lab data can predict which stroke patients may not benefit from clot removal.
Peripheral nerve lesion types in patients with primary Sjögren's syndrome
Nerve damage affects many people with Sjögren's syndrome
This retrospective observational study of 92 patients with primary Sjögren's syndrome examined the clinical and serological characteristics …
New data shows that nerve issues are common in Sjögren's syndrome patients and may follow a specific pattern.
Preconception environments linked to pregnancy-related brain remodeling and better maternal mental health in a Singaporean cohort
Preconception lifestyle choices may shape brain resilience during pregnancy
This observational cohort study of 194 preconception participants and 61 postpartum participants from Singapore examined how lifestyle and…
A Singapore study links healthy preconception habits to better brain changes during pregnancy and lower anxiety for moms and kids.
Personalized Feature Statistics framework characterizes genetic variant effects in Alzheimer's Disease across diverse ancestries
Genetic risk for Alzheimer's varies by ancestry in new analysis
This cohort study analyzed ancestrally diverse cohorts in the Alzheimer's Disease Sequencing Project (ADSP).
A new analysis shows genetic risk for Alzheimer's disease changes across different ancestry backgrounds, offering a clearer view of individu…
Self-efficacy and age associated with disability acceptance trajectories in hypertensive intracerebral hemorrhage patients
Belief in yourself helps people accept life after brain bleeds
This prospective longitudinal study of 114 patients with hypertensive intracerebral hemorrhage examined the developmental trajectory of disa…
New research shows that your confidence in your own abilities can help you navigate the difficult journey of accepting a disability.
Observational study finds higher hostility bias in genetic generalised epilepsy
People with genetic generalised epilepsy show higher hostility bias than healthy controls
This observational study compared attributional bias in 96 participants with genetic generalised epilepsy, temporal lobe epilepsy, and healt…
A new study found that people with genetic generalised epilepsy often blame others more than healthy people do, a sign of social difficulty.
Soft robotic exoskeleton training improved gait speed and stride length in people with Parkinson disease over four weeks
Soft robotic suits helped people with Parkinson disease walk faster and move better
This randomized controlled pilot study enrolled 56 people with Parkinson disease.
A pilot study found that adding soft robotic exoskeleton training to standard rehab improved walking speed, stride length, and balance in pe…