Thalamic MRS and cervical DTI changes in cervical spondylotic myelopathy versus healthy controls
Can brain scans show how bad a neck injury hurts your spinal cord?
This prospective study compared 93 patients with cervical spondylotic myelopathy (CSM) and 67 healthy controls using cervical MRI, bilateral…
Brain scans of the thalamus reveal lower signals in patients with neck injuries, offering a new way to measure how bad spinal cord damage is…
Sudden sensorineural hearing loss risk factors in ankylosing spondylitis patients on adalimumab plus methotrexate
Could long-term arthritis treatment raise your risk of sudden hearing loss?
This retrospective case-control analysis drew on 2,564 ankylosing spondylitis patients at Henan Provincial People's Hospital (2015-2024), co…
Patients with long-term ankylosing spondylitis taking adalimumab and methotrexate are more likely to experience sudden hearing loss than tho…
Posdinemab shows linear pharmacokinetics and predicted tau reduction in Phase 1 AD study
New Alzheimer's Drug Could Silence Brain's Toxic Tangles
This Phase 1 mechanistic population pharmacokinetic-pharmacodynamic model evaluated posdinemab in 69 healthy adults and participants with Al…
A new Alzheimer's drug could silence toxic brain tangles before memory loss worsens, offering hope for millions of families facing early-sta…
Volitional fast inspiration increased MEP and SEP amplitudes and muscle force in stroke patients compared to spontaneous breathing.
Could a simple breath boost your recovery after a stroke?
This withdrawn case-control study compared volitional fast inspiration against spontaneous breathing and fast expiration in 52 healthy volun…
A simple fast breath before moving muscles boosted force by 16 to 18 percent in stroke patients, though the study was withdrawn before offic…
Review of bilingualism effects on naming performance in Catalan-Spanish speakers with cognitive impairment
Why Knowing Two Languages Changes the Story
This narrative review synthesizes observational evidence on bilingualism and naming performance in Catalan-Spanish bilinguals with Alzheimer…
Active bilinguals with early memory loss made more naming errors than those who only knew one language well, showing that fluency matters fo…
Observational study finds autonomic dysfunction in idiopathic hypersomnia versus narcolepsy and controls
Do you feel exhausted all day? New data shows your heart may struggle when you stand up.
This observational study assessed autonomic nervous system function in adults with idiopathic hypersomnia (IH), type 1 narcolepsy (NT1), and…
People with idiopathic hypersomnia have hearts that race faster when standing and struggle to sweat properly, revealing hidden autonomic ner…
Brain reserve moderates AD pathology associations with cognitive function in cognitively unimpaired adults
Younger Brains Shield Memory From Early Alzheimer's
This cross-sectional analysis of baseline data from a multisite randomized clinical trial examined 621 cognitively unimpaired, physically in…
Your brain's "fitness level" can act like a shield, protecting your memory even when early Alzheimer's proteins are present.
Cortical Superficial Siderosis Burden Predicts Hemorrhage and Poor Outcomes After Stroke Thrombolysis
New Brain Scan Marker Predicts Bleeding Risk Before Treatment
A substudy of the AcT trial (alteplase versus tenecteplase) evaluated radiological Boston CAA criteria and constituent markers in 482 thromb…
A specific brain scan pattern predicts dangerous bleeding after clot-busting drugs, helping doctors decide who needs fast treatment to save …
Mini-review synthesizes dementia risk and cognitive trajectories in individuals with schizophrenia.
Do people with schizophrenia face a higher risk of dementia, and what does that mean for their care?
This mini-review examines the relationship between schizophrenia and dementia, covering Alzheimer's disease, vascular dementia, and other fo…
People with schizophrenia face a two- to threefold higher risk of dementia, but it's not a direct path to Alzheimer's—brain development, agi…
Systematic review finds gut microbiome dysbiosis associated with ALS progression
Could gut bacteria changes be linked to ALS, or just happen alongside it?
This systematic review with narrative synthesis examined 61 studies on gut microbiome alterations in ALS. It found reduced microbial diversi…
People with ALS often show reduced gut bacteria diversity, but it is still unclear if these changes cause the disease or simply happen along…
Mobile respiratory training improved lung function in acute stroke patients with respiratory dysfunction.
Mobile respiratory training improved lung function in hospitalized stroke patients with breathing issues
This single-center randomized controlled trial enrolled 40 inpatients with acute stroke and respiratory dysfunction. Participants receiving …
A mobile breathing app helped hospitalized stroke patients improve lung capacity by 0.77 liters compared to standard care alone.
Cerebral infarction common in tuberculous meningitis and linked to disease severity and arterial occlusion
Could blood thinners or specific treatments make brain strokes worse in severe meningitis?
This secondary analysis of the ACT-TBM randomized trial examined 226 patients with tuberculous meningitis at two tertiary centers in India. …
Patients with tuberculous meningitis and blocked arteries were much more likely to develop strokes, especially if they received modified tub…