FDA Approves Onapgo (apomorphine) for Motor Fluctuations in Advanced Parkinson's
FDA approves Onapgo for motor fluctuations in advanced Parkinson's disease.
FDA approved Onapgo (apomorphine hydrochloride) subcutaneous infusion for motor fluctuations in adults with advanced Parkinson's disease. Th…
The FDA approved Onapgo (apomorphine hydrochloride) for adults with advanced Parkinson's disease who have motor fluctuations. It is given as…
Narrative review links personality traits to Alzheimer's disease risk and cognitive outcomes
Personality traits like neuroticism may signal higher Alzheimer's risk
This narrative review synthesizes evidence on personality traits and Alzheimer's disease. It finds high neuroticism and low conscientiousnes…
A review of studies suggests personality traits such as neuroticism and conscientiousness are linked to Alzheimer's disease risk and cogniti…
Narrative review links exercise and sleep architecture to executive function in older adults
Sleep and exercise work together to protect brain function in older adults
This narrative review examines theoretical pathways connecting exercise and sleep architecture to executive function in middle-aged and olde…
A review explains how sleep and exercise jointly support brain health in middle-aged and older adults, offering hope for better cognitive fu…
Restrictive platelet thresholds reduce transfusions without increasing death or bleeding risk in thrombocytopenic neonates
Restrictive transfusion thresholds reduce blood use in newborns without increasing death risk
A systematic review of 856 neonates found that restrictive platelet transfusion thresholds significantly reduced transfusion use. Crucially,…
Newborns with low platelet counts get fewer transfusions when doctors use stricter rules, saving blood without raising death or bleeding ris…
Systematic review finds facial expression recognition shows promise for stroke diagnosis and rehabilitation monitoring
AI reads faces to detect stroke with up to 98% accuracy
This systematic review of 9 studies found that facial expression recognition (FER) technology achieved diagnostic accuracies of 82-98% for s…
A new review finds facial recognition AI can spot stroke with 82-98% accuracy, and track rehab progress with 99.81% accuracy. But real-world…
Narrative review synthesizes neural activation patterns in the caudate nucleus and dorsal striatum during gustatory stimulation
Brain scans show taste links to reward areas in health and disease
This narrative review examines how the caudate nucleus and dorsal striatum activate during gustatory stimulation across different metabolic …
A review suggests brain regions linked to taste also process reward and emotion, offering new perspectives on chemosensation and potential i…
Narrative review outlines multimodal decision-making for EGFR-mutant NSCLC with leptomeningeal metastasis
Doctors outline a pathway for treating lung cancer that spreads to the brain
This narrative review addresses patients with EGFR-mutant non-small cell lung cancer who develop resistance to tyrosine kinase inhibitors an…
This review outlines a clinical pathway to help physicians personalize treatment for lung cancer patients with brain spread.
Meta-analysis finds pharmacologic therapies improve RLS in hemodialysis patients
Medications help restless legs in dialysis patients
This systematic review and meta-analysis synthesized evidence on pharmacologic therapies for restless legs syndrome in adults undergoing mai…
A review of studies shows certain medicines can ease restless legs and improve sleep for people on dialysis. Some options work better than o…
Deep brain stimulation improves motor function and reduces levodopa needs in Parkinson's disease patients regardless of GBA mutation status
Deep brain stimulation helps Parkinson's patients but GBA mutation carriers face faster cognitive decline
A systematic review found that deep brain stimulation significantly enhanced motor function and lowered medication requirements for Parkinso…
Deep brain stimulation improves movement and lowers medication needs for Parkinson's patients, yet those with GBA mutations show faster thin…
Umbrella review synthesizes evidence on sexsomnia, a disorder of arousal from N2/N3 sleep
Sleep Deprivation And Alcohol Linked To Sexsomnia In Review
This umbrella review analyzed nine existing reviews on sexsomnia. It characterizes the disorder as emerging from N2/N3 sleep with sexual aut…
A review of nine studies links sleep deprivation and alcohol to sexsomnia, a sleep disorder with no standardized diagnostic criteria yet.
Systematic review compares CEA, CAS, and TCAR for carotid artery stenosis stroke risk
New analysis compares stroke treatments for carotid artery stenosis
This systematic review and network meta-analysis evaluates carotid endarterectomy (CEA), carotid artery stenting (CAS), and trans-carotid ar…
A review of 55 studies finds carotid endarterectomy lowers short-term stroke risk compared to stenting, while stenting may lower nerve injur…
Meta-analysis finds remote ischemic conditioning modestly improves functional independence in acute ischemic stroke
Remote conditioning may modestly boost stroke recovery
This meta-analysis of 5301 patients with acute ischemic stroke found that remote ischemic conditioning (RIC) was associated with a modest in…
A simple arm cuff treatment could slightly improve independence after a stroke, but the benefit is small and uncertain.