Climate change disproportionately impacts African population health despite minimal global greenhouse gas contributions
Climate change creates disproportionate health risks for people in Africa
This narrative review examines the impact of climate change on health outcomes for populations in Africa. The authors argue that current glo…
People in Africa face severe health risks from climate change despite contributing the least to global emissions, highlighting a major gap i…
Tigertriever associated with higher reperfusion rates in large vessel occlusion stroke compared to stent-retrievers
Tigertriever device shows higher success in treating large stroke blockages
This systematic review and meta-analysis of 476 patients found that the Tigertriever was associated with a significantly higher rate of succ…
A new type of adjustable medical device may improve blood flow for patients with major strokes compared to standard stent-retrievers.
FDA Approves Tyruko (natalizumab) for Relapsing Forms of Multiple Sclerosis and Crohn's Disease
FDA approves new drug Tyruko for multiple sclerosis and Crohn's disease.
The FDA approved Tyruko (natalizumab) for relapsing forms of multiple sclerosis and for moderately to severely active Crohn's disease. The d…
The FDA approved Tyruko (natalizumab) to treat relapsing forms of multiple sclerosis and moderately to severely active Crohn's disease in ad…
CRISPR/Cas9 screening identifies host factors and conserved networks for multiple livestock and poultry viruses
New screening identifies common pathways for several livestock viral diseases
This systematic review evaluates CRISPR/Cas9 functional screening to identify host factors involved in viral entry, replication, and egress …
Scientists used gene editing tools to find shared biological pathways that multiple livestock viruses use to infect and spread through anima…
α-Synuclein-lysosome axis central to Parkinson's pathogenesis, systematic review finds
Parkinson's protein and lysosome link may guide new treatments
This systematic review synthesizes molecular evidence that the interplay between α-synuclein and lysosomal function is a central mechanism u…
A review reveals how a protein called α-synuclein and lysosomes interact in Parkinson's, pointing to potential new therapies.
Gastrodin, intranasal insulin, and cognitive training show greatest preventive effectiveness for postoperative cognitive dysfunction after cardiac surgery
Insulin, Gastrodin, and Training May Protect Brain After Heart Surgery
A systematic review and Bayesian network meta-analysis of 46 RCTs (9,928 patients) ranked 20 strategies for preventing postoperative cogniti…
A review of 46 trials suggests certain drugs and cognitive training may help prevent confusion and memory loss after cardiac surgery.
Music intervention significantly improves GCS scores and awakening rates in patients with disorders of consciousness
Music Intervention May Improve Awareness in Patients with Consciousness Disorders
This meta-analysis of 12 randomized controlled trials involving 926 patients found that music interventions are associated with higher GCS s…
Music therapy shows a link to improved consciousness scores and higher awakening rates for patients with disorders of consciousness.
Multidimensional vHIT saccadic parameters provide complementary information for diagnosing central vestibular disorders
New ways to tell the difference in balance disorders
This narrative review examines the clinical utility of video head impulse test (vHIT) saccadic parameters in managing central vestibular dis…
Doctors can better distinguish between different types of dizzy spells by looking at specific eye movements during head tests.
TMS targeting the ventral attention network may address heterogeneity in alcohol use disorder with depression
New target for brain stimulation in alcohol and depression
This mini review explores transcranial magnetic stimulation (TMS) targeting the ventral attention network (VAN) for individuals with alcohol…
A new focus on the ventral attention network could help create more precise treatments for people facing both alcohol use disorder and depre…
Acupoint stimulation reduces OCD symptoms by 3.14 points on Y-BOCS in meta-analysis
Acupoint stimulation shows reduction in obsessive-compulsive disorder symptoms
A meta-analysis of 23 RCTs with 1,713 participants found that acupoint stimulation (electroacupuncture, acupuncture, transcutaneous electric…
New analysis of 23 trials suggests that acupoint stimulation can help reduce symptoms for people living with obsessive-compulsive disorder.
FDA Approves Subvenite (lamotrigine) for Epilepsy and Bipolar Disorder
FDA approves Subvenite for epilepsy and bipolar disorder maintenance.
FDA approved Subvenite (lamotrigine) for adjunctive therapy of partial-onset, PGTC, and Lennox-Gastaut seizures in patients aged 2 years and…
The FDA approved Subvenite (lamotrigine) to treat certain types of seizures in adults and children age 2 and older, and to delay mood episod…
Sedative-hypnotic use associated with OR 1.29 for incident Alzheimer's Disease
Meta-analysis links sedative-hypnotic drug use to higher Alzheimer risk
This meta-analysis of observational cohort and nested case-control studies involving 721,354 adults without baseline dementia found that sed…
A large study suggests a link between the use of common sleep medications like benzodiazepines and an increased risk of developing Alzheimer…