Resting-state fMRI shows brain activity differences in women with functional constipation and stress urinary incontinence
Does stress incontinence and constipation change how your brain works?
A cohort study of 34 female patients with functional constipation and stress urinary incontinence (FCon-SUI), 24 with functional constipatio…
Women with both constipation and incontinence show unique brain activity patterns linked to movement control and visual processing that diff…
Prospective cohort study links age, GCS, and CT scores to posttraumatic confusional state duration in TBI patients
How Long Is the Confusion After a Brain Injury
A prospective inception cohort of 424 neurosurgical patients with moderate or severe traumatic brain injury found that shorter PTCS duration…
Age and injury severity, not past education or brain health, determine how long confusion lasts after a serious head injury.
Genetic mutations in febrile sensitivity epilepsy correlate with earlier onset and specific diagnoses in children
Fever-Triggered Seizures in Children Trace Back to Specific Genes
This retrospective cohort study examined 30 gene-positive cases and 31 gene-negative controls at Wuxi Children's Hospital.
Half of children with fever-triggered seizures carry specific gene mutations that help doctors predict which treatments will work and which …
Targeted nanopore sequencing and biomarkers show diagnostic and prognostic value in intracranial infections
A DNA-Sequencing Tool Is Changing How Brain Infections Get Diagnosed
A retrospective cohort study of 255 patients with suspected intracranial infections found that targeted nanopore sequencing identified commo…
A fast genetic test paired with routine blood markers helps doctors quickly identify the cause of brain infections, potentially reducing tim…
Vascular risk factors and diagnostic findings in young stroke patients across sixteen MENA centers
Young Adults Are Having Strokes — And the Causes May Surprise You
This retrospective cohort study examined 3,971 young adults with stroke across nine Middle East and North Africa countries.
High blood pressure and diabetes are driving strokes in young adults across the Middle East and North Africa, creating distinct risks that d…
Retrospective study of 17 Caucasian women with Sjogren disease and anti-synthetase syndrome shows ILD involvement in 82%
Sjögren's and Lung Disease: A New Warning Sign
This multicentre retrospective study examined 17 female patients of Caucasian ethnicity across three Italian referral centres.
A shared protein links Sjögren's dry mouth and eyes to lung disease, helping doctors identify dangerous breathing issues often missed in ear…
Longer road distance to stroke centers linked to higher interfacility referrals in Colombian AIS patients
Living Far From a Stroke Center Raises Your Risk of Dying
A retrospective cohort study of 529 adult acute ischemic stroke patients in Colombia found that increased road distance to comprehensive str…
Where you live when a stroke strikes may matter almost as much as the stroke itself — and this study shows just how large that gap can be.
VeraBIND Tau assay predicts tau-PET positivity in older adults with high sensitivity and specificity
A Blood Test That Sees Alzheimer's Before Memory Slips
This observational study evaluated the VeraBIND Tau assay against plasma pTau217 in 145 older adults, including cognitively unimpaired and i…
A new blood test detects active Alzheimer's tau protein years before memory slips, offering a simple flu-style draw to spot the disease in p…
Drosophila models show SYT1 variant D310N causes more severe Baker-Gordon syndrome phenotypes than D366E
New Gene Mutation Explains Why Some Kids Struggle More
This study utilized Drosophila models to compare clinical phenotypes associated with two SYT1 variants, D310N and D366E, in the context of B…
A new gene mutation causes Baker-Gordon syndrome to be much worse, revealing why some children face severe symptoms while others do not.
FDA Approves Lamotrigine Tablets (lamotrigine) for Epilepsy and Bipolar Disorder Maintenance
The FDA has approved a drug called lamotrigine for epilepsy and bipolar disorder treatment
Lamotrigine tablets were approved as adjunctive therapy for partial-onset seizures, PGTC seizures, and Lennox-Gastaut syndrome in patients a…
The FDA has approved lamotrigine to help control seizures in children as young as two and maintain mood stability for adults with bipolar di…
FDA Approves Valproic Acid Capsules (valproic acid) for monotherapy and adjunctive therapy of complex partial seizures and absence seizures
The FDA has approved a new epilepsy drug called Valproic Acid Capsules for treating seizures
Valproic Acid Capsules were approved for monotherapy and adjunctive therapy of complex partial seizures, and sole and adjunctive therapy of …
The FDA approved Valproic Acid Capsules to treat complex partial and absence seizures in people aged 10 and older.
FDA Approves Rezenopy (naloxone) for Emergency Treatment of Opioid Overdose
FDA approves new nasal spray called Rezenopy for emergency treatment of opioid overdose
The FDA approved Rezenopy nasal spray for emergency treatment of known or suspected opioid overdose in adult and pediatric patients.
FDA approves new nasal spray Rezenopy to quickly reverse opioid overdose in adults and children when someone shows slow breathing or is unre…