Bibliometric analysis of ICU-AW literature reveals expanding global research focus on early rehabilitation and nutrition
How is research on ICU weakness changing, and what does this mean for patient care?
This bibliometric analysis examined 1,449 publications from the Web of Science Core Collection and 648 from PubMed regarding intensive care …
Research on ICU weakness is shifting toward early detection, quick rehabilitation, and nutrition support as global studies grow.
Plastic changes in brainstem reticular formation may be involved in spasticity onset across stroke and spinal cord injury
Could brainstem plastic changes trigger spasticity in stroke and spinal cord injury patients?
This systematic review examined pathophysiological similarities in spasticity among humans, primates, and rodents.
Spasticity after stroke or spinal cord injury may stem from plastic changes in the brainstem, though evidence remains limited and controvers…
Rare variants in 44 dystonia genes show no major contribution to Parkinson's disease risk overall
Rare genetic variants linked to dystonia do not appear to significantly increase Parkinson's disease risk overall
This meta-analysis examined rare genetic variants in 5,315 Parkinson's disease patients and 36,902 controls from whole-genome sequencing dat…
Rare genetic variants linked to dystonia do not appear to significantly increase Parkinson's disease risk overall, according to a large gene…
Gut Metabolite Levels Associate with Outcomes After Aneurysmal Subarachnoid Hemorrhage
Can early blood tests predict brain injury after a severe brain bleed?
A prospective observational cohort of 80 patients with aneurysmal subarachnoid hemorrhage found lower levels of specific gut-derived metabol…
Low levels of specific gut chemicals in early blood tests may signal delayed brain injury after a severe brain bleed, offering a potential w…
Luteolin shows neuroprotective potential in preclinical models for Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis
Luteolin shows potential benefits in early studies for neurodegenerative diseases
This review of preclinical studies and preliminary clinical observations suggests luteolin may reduce neuroinflammation and improve function…
Luteolin may help slow brain decline in Alzheimer's and Parkinson's by calming inflammation and boosting antioxidant defenses in early studi…
Endolymphatic hydrops severity shows no significant association with cochlear or vestibular nerve volumes in 108 patients
Does the severity of inner ear fluid swelling actually shrink your hearing nerves?
This cohort study evaluated 108 patients with clinically and radiologically confirmed endolymphatic hydrops to assess volumetric changes in …
MRI scans show that severe inner ear fluid swelling does not shrink hearing nerves or cause symptoms like dizziness or ringing in the ears.
Spatial coupling of enlarged perivascular spaces and white matter lesions observed across Alzheimer's disease continuum stages
Do enlarged brain spaces link to early Alzheimer's changes?
This observational cohort study analyzed participants from the Alzheimer's Disease Neuroimaging Initiative dataset categorized by cognitive …
People with early Alzheimer's memory issues have swollen brain drainage tubes right next to damaged areas, suggesting these changes happen b…
Active bilingualism associated with better neuropsychological function and biomarker profiles in Alzheimer's disease compared to passive bilingualism
Do speaking two languages help protect your brain from Alzheimer's disease?
This cohort study examined Spanish-Catalan bilinguals with biomarker-confirmed Alzheimer's disease.
People with Alzheimer's who actively speak two languages show better brain function and lower disease markers than those who do not.
Pipeline Embolization Device in Small Vessels (<2 mm) Shows 52% 1-Year Occlusion, 16.9% Ischemic Events
Study of Pipeline Device in Small Vessels Shows Mixed Results
A retrospective multicenter cohort of 71 patients with intracranial aneurysms in parent vessels <2 mm found a 1-year complete occlusion rate…
A Pipeline device in tiny brain vessels closed 80% of aneurysms long-term but caused strokes in 17% of patients, with longer devices raising…
Early nutrition and rehabilitation protocol associated with better outcomes in severe subarachnoid hemorrhage
Can early feeding and rehab help severe brain bleed survivors recover better?
A retrospective cohort study of 102 patients with severe SAH (Hunt–Hess grade III–V) found that combined early enteral nutrition (within 48 …
Starting feeding and rehab within three days helped severe brain bleed survivors recover better, spend less time in the hospital, and avoid …
Earlier endovascular therapy within 24 hours associated with smaller infarct and better outcomes in LVO stroke
Does waiting longer for stroke treatment cause more brain damage and worse recovery?
This prospective cohort study evaluated 216 patients with anterior circulation large-vessel occlusion stroke treated with endovascular thera…
Waiting longer for stroke treatment causes more dead brain tissue and leaves fewer patients able to live independently after 90 days.
ESKD Patients Had Higher ED Hospitalization, Mortality During COVID-19 Pandemic in South Korea
Did the pandemic make emergency visits and deaths worse for adults with end-stage kidney disease?
A retrospective cohort study of 159,456 ED visits by adult ESKD patients in South Korea found increased hospitalization (aOR 1.054) and mort…
Adults with end-stage kidney disease faced higher risks of hospitalization and death during the pandemic, while emergency visits increased f…