Systematic review on fermented bread and iron bioavailability in healthy or iron-deficient participants
Sourdough Bread Might Not Boost Iron Like Experts Thought
This systematic review synthesized evidence from 8 human intervention studies on sourdough or regular bread fermentation and iron bioavailab…
• Short term iron absorption improves but long term stores drop • Iron deficient adults and anemic children could benefit differently • Not …
GLP-1 receptor agonists show greater weight loss in women than men across multiple trials
Women Lose More Weight on GLP-1 Drugs Than Men Do
This systematic review and meta-analysis examined weight changes among adults with obesity, diabetes, or cardiovascular disease treated with…
• Women lose 11% weight versus 7% for men on these drugs • Helps adults using Wegovy Ozempic and similar weight loss medications • Works sam…
Low-fat or low-carb diet weight loss shows modest appendicular lean tissue decrease in adults with obesity
Most People Lose Very Little Muscle During Diet Weight Loss
This randomized controlled trial in 374 adults with obesity found that a 6-month healthy low-fat or low-carbohydrate diet-based weight-loss …
Worried about losing muscle while dieting? A new study tracking 374 people found that after six months of weight loss, muscle loss was surpr…
Meta-analysis shows combined bariatric and body contouring surgery improves quality of life and weight loss versus bariatric surgery alone
Adding body contouring surgery after weight loss improves quality of life and weight loss
This systematic review and meta-analysis evaluated patients undergoing bariatric surgery alone versus those receiving combined bariatric and…
A large analysis shows adding body contouring surgery after weight loss surgery improves quality of life, body image, and total weight loss …
Weight Regain Reverses Caloric Restriction Benefits on Insulin-IGF-1 Pathway and Biological Age
Weight Regain Undoes Caloric Restriction Benefits For Diabetes Risk
This post hoc analysis of the CALERIE-2 trial examined 190 participants who underwent 25% caloric restriction or control diet.
Losing weight helps control diabetes risk, but gaining those pounds back undoes the hormonal benefits and reverses progress made during the …
Two-year caloric restriction attenuated biological age increases across multiple organ systems in a randomized trial
Eating Less Slows Aging in Heart and Metabolism Systems
This Phase 2 randomized controlled trial evaluated 185 participants assigned to sustained caloric restriction or an ad libitum diet.
Eating less food may actually slow down aging in your heart and metabolism while keeping other organs stable.
Semaglutide reduces insulin dose in adults with type 1 diabetes and obesity
Semaglutide Cuts Insulin Needs By Half In Type 1 Diabetes
A post hoc analysis of an RCT found that semaglutide 1 mg/week significantly reduced total daily insulin dose by 22.6% over 26 weeks in adul…
Semaglutide reduces insulin needs quickly in type 1 diabetes patients, offering a new hope for better blood sugar control and weight managem…
Systematic Review and Meta-Analysis: Bariatric Surgery Reduces Low Back Pain in Morbid Obesity
Metabolic surgery reduces back pain and improves spinal health in morbidly obese adults
This systematic review and meta-analysis of 390 morbidly obese adults found that metabolic and bariatric surgery significantly reduced low b…
Metabolic surgery significantly reduced back pain and improved quality of life for morbidly obese patients with low back pain, though spinal…
Resistance exercise and high protein diet improved metabolic flexibility in older men over 12 weeks
Resistance exercise and high protein diet improved metabolic flexibility in older men
This randomized controlled trial involved 33 older men.
A 12-week trial found that resistance exercise and high protein diet improved metabolic flexibility in older men compared to doing nothing.
Wholegrain rye diets improve metabolic markers but not weight loss in overweight adults
Wholegrain rye lowers inflammation better than refined wheat for weight loss diets
This 12-week randomized trial compared hypocaloric diets with wholegrain rye versus refined wheat in 255 adults with overweight or obesity.
Switching to wholegrain rye while dieting may lower inflammation and improve gut bacteria even if weight loss is the same
Energy restriction with ultra-processed food restriction yields greater weight loss than generic energy restriction in obesity
Low-Processed Food Diet May Help People With Obesity Lose More Weight
This randomized clinical trial enrolled 148 individuals with obesity and compared energy restriction associated with ultra-processed food re…
A trial found that restricting ultra-processed foods alongside calorie limits helped people with obesity lose more weight and reduce ultra-p…
Exploratory analysis of RYGB and SG shows variable LDL cholesterol response in patients with obesity and high LDL cholesterol
Two bariatric surgeries lower cholesterol through completely different biological paths
This exploratory analysis of a randomized clinical trial (BASALTO) evaluated 30 patients with obesity and high LDL cholesterol undergoing Ro…
New research shows that two popular weight loss surgeries lower bad cholesterol in very different ways that could change how doctors pick a …