Exercise interventions may improve adiposity and physical function in middle-aged or older adults with sarcopenic obesity
Exercise helps middle-aged and older adults with sarcopenic obesity
This umbrella review of systematic reviews synthesized evidence on exercise-based interventions for middle-aged and older adults with sarcop…
New research shows that exercise programs can improve body composition and physical function for older adults struggling with both muscle lo…
High glycemic variability in ICU patients linked to 2.29-fold higher mortality risk
Blood sugar swings linked to higher death risk in ICU patients
This meta-analysis of 36 studies (123,911 patients) found that short-term glycemic variability metrics, particularly standard deviation and …
Wide swings in blood sugar may raise death risk for ICU patients, a large review of 36 studies finds.
Fish consumption increases vitamin D levels by 4.08 nmol/L in children across randomized trials
Eating fish may help improve vitamin D levels in growing children
This meta-analysis of randomized controlled trials evaluated the impact of fish consumption on micronutrient status in children aged 2 to 14…
New data shows that children who eat fish have higher vitamin D levels. This nutrient is vital for strong bones and healthy growth.
Food insecurity linked to poorer diet and higher obesity risk in older adults
Food Insecurity Linked to Poorer Diet and Obesity in Older Adults
This narrative review synthesizes evidence linking food insecurity and financial hardship to poorer diet quality and higher odds of overweig…
Older adults facing food insecurity eat worse and are more likely to be obese, a review finds.
Semaglutide associated with 35.2% of weight loss as lean mass versus 26.2% with lifestyle interventions
New analysis shows weight loss drugs and lifestyle changes affect muscle loss similarly
This systematic review and meta-analysis evaluated 15 782 adults with overweight or obesity receiving incretin-based therapies or intensive …
A large review of 15,782 adults found that weight loss drugs and lifestyle changes led to similar proportions of muscle loss during weight r…
Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
Pre-existing health conditions may slightly reduce weight loss after surgery
A meta-analysis of twenty-three studies reveals that mental illness, diabetes, and sleep apnea are associated with slightly lower weight los…
Adults with mental illness or diabetes before surgery saw slightly less weight loss. Other conditions like high blood pressure did not affec…
Vitamin D's role in antifungal immunity remains uncertain due to species differences
Primate biology limits how rodent vitamin D data applies to human fungal infections
This narrative review examines the potential role of vitamin D in antifungal immunity. The authors synthesize evidence from animal models bu…
A review notes that species differences and model limitations prevent direct translation of rodent findings to human fungal disease treatmen…
NAD+ repletion via NMN or NR shows context-dependent effects on muscle stem cell homeostasis and sarcopenia
NAD+ boosters may help muscle stem cells fight aging weakness
This systematic review synthesizes nearly 60 representative preclinical and clinical studies on NAD+ repletion for sarcopenia. The authors d…
A review of nearly 60 studies suggests NAD+ precursors like NMN or NR could support muscle stem cells and reduce oxidative stress in sarcope…
Tirzepatide maximum tolerated dose leads weight reduction ranking in obesity network meta-analysis
New analysis shows weight loss drugs work best for adults with obesity without diabetes
This systematic review and network meta-analysis of 14,059 adults with obesity without diabetes ranked GLP-1 receptor agonists and a dual ag…
A large review of many studies found that specific injectable medicines help adults lose weight. Tirzepatide worked best, but all options re…
Insulin degludec/liraglutide ranks highest for HbA1c reduction with SUCRA value of 89.4%
Comparing Combination Diabetes Drugs for Blood Sugar Control
This network meta-analysis evaluated 12,815 patients with type 2 diabetes to compare fixed-ratio combination products and their individual c…
A review of 12,815 patients found that insulin degludec/liraglutide may be best for lowering blood sugar, but has more side effects than oth…
Modulating endogenous PYY expression offers a theoretical basis for individualized obesity management strategies
Ways to boost body's fullness hormone for weight control
This narrative review discusses modulating endogenous PYY expression via dietary interventions, bariatric surgery, exercise therapy, and phy…
This review explores how diet, surgery, and exercise can raise PYY levels, helping people feel fuller and manage weight more effectively.
Vitamin D improves strength and reduces injuries in dancers, while iron lowers anemia prevalence
Dancers take many supplements, but benefits are often unproven and risks remain unclear
This systematic review of dietary supplement and medication use in 654 female and 86 male professional and pre-professional dancers found vi…
Dancers use many supplements and painkillers, yet benefits are limited and potential health risks need more study before we can trust them.